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Alexa Fluor® 647 anti-mouse CD85k (gp49 Receptor)

Alexa Fluor® 647 anti-mouse CD85k (gp49 Receptor)

種類 144905
通常価格
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説明

gp49, also known as ILT3, gp49b1 or CD85k, is a 49 kD glycoprotein expressed on activated NK cells and myeloid cells. It structurally resembles killer inhibitory receptors (KIR). gp49B is a type I membrane protein belonging to the Ig superfamily and contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), while gp49A is a truncated molecule without ITIM. Upon activation following interaction with integrin avb3, the cytoplasmic tail associates with SHP-1 and SHP-2, which results in downregulation of cell activation and cytokine production.  


PRODUCT DETAILS

Clone: H1.1

Antibody Type: Monoclonal

Reactivity: Mouse

Format: Alexa Fluor 647

Host: Armenian Hamster

Isotype: IgG

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS



Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.