CD18 is a 95 kD protein, also known as integrin β₂ subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and α_Xβ₂, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

PRODUCT DETAILS

Clone: M18/2

Antibody Type: Monoclonal

Reactivity: Mouse

Format: Alexa Fluor 594

Host: Rat

Isotype: IgG2a, κ

Applications: IHC-F - Quality tested FC, 3D IHC- Verified

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.