The antibody SYK-01 reacts with protein tyrosine kinase p72Syk (Syk; an intracellular antigen), which is required for the transduction of signals through the B cell antigen receptor (BCR) and the high affinity IgE receptor (FcepsilonRI).

PRODUCT DETAILS

Clone: SYK-01

Specificity: SYK

Reactivity: Human|Mouse, Rat

Format: Purified

Isotype: Mouse IgG1

Application: IP, WB, IHC-P, ICC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Western blotting: Recommended dilution: 1-2 μg/ml.
Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/ml; positive tissue: tonsil B cells.

REFERENCES

1. Parravicini V, et al. 2002. Nat Immunol 3:741-8.
2. Manetz TS, et al. 2001. Mol Cell Biol 21:3763-74.
3. Ma H, et al. 2001. J Immunol 166:1507-16.
4. Osicka R, et al. 2015. Elife 4:e10766.
5. Heneberg P, et al. 2006. Eur J Immunol 36:2795-806.
6. Hálová I, et al. 2002. Int Immunol 14:213-23.
7. Arudchandran R, et al. 2000. J Exp Med 191:47-60.

For research use only. Not intended for use in diagnostic procedures.