The antibody PAG-C1 recognizes an epitope located in the intracellular C-terminal domain of Csk-binding protein (Cbp / PAG), a 46 kDa ubiquitously expressed transmembrane adaptor protein present in membrane rafts (glycosphingolipid-enriched microdomains), which however migrates on SDS PAGE gels anomalously as an 80 kDa molecule.

PRODUCT DETAILS

Clone: PAG-C1

Specificity: PAG1

Reactivity: Human|Mouse, Bovine, Rat

Format: Purified

Isotype: Mouse IgG2b

Application: IP, WB, IHC-P

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Immunohistochemistry (paraffin sections): Positive tissue: appendix (germinal center of lymphatic follicle), heat-mediated antigen retrieval in citrate buffer pH 6.1.
Immunoprecipitation: Positive control: RAJI human Burkitt lymphoma cell line.

REFERENCES

1. Brdicka T, et al. 2000. J Exp Med 191:1591-604.
2. Vang T, et al. 2003. J Biol Chem 278:17597-600.

For research use only. Not intended for use in diagnostic procedures.