The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody preferentially recognizes CD243 in the process of transporting substrate.

PRODUCT DETAILS

Clone: UIC2

Specificity: CD243

Reactivity: Human

Format: Purified

Isotype: Mouse IgG2a, k

Application: FC, IP, IHC-P

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Immunohistochemistry (paraffin sections): Heat mediated antigen retrieval in citrate buffer pH 6.
Flow cytometry: Recommended dilution: 1-4 µg/ml

REFERENCES

1. Kelley DJ, et al. 1993. Arch Otolaryngol Head Neck Surg 119:411-4.
2. Collnot EM, et al. 2010. Mol Pharm 7:642-51.
3. Goda K, et al. 2007. J Pharmacol Exp Ther 320:81-8.
4. Mechetner EB, et al. 1992. Proc Natl Acad Sci U S A 89:5824-8.

For research use only. Not intended for use in diagnostic procedures.