The antibody MEM-240 recognizes an extracellular epitope between amino acids 698-1262 of CD222 (IGF2 receptor), a ubiquitously expressed 250 kDa multifunctional type I transmembrane protein. The majority of CD222 is found in the late endosomal/prelysosomal compartment, 5-10% in the plasma membrane and the truncated (220 kDa) form of CD222 is present in human and bovine serum.

PRODUCT DETAILS

Clone: MEM-240

Specificity: CD222

Reactivity: Human

Format: Purified

Isotype: Mouse IgG1

Application: FC, IP, WB, FC-IC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Extracellular and intracellular staining. Recommended dilution: 2-6 μg/ml.
Western blotting: non-reducing conditions. Recommended dilution: 1-2 μg/ml.

REFERENCES

1. Wood RJ, et al. 2008. J Biol Chem 283:4165-76.
2. Gasanov U, et al. 2006. Infect Immun 74:566-77.
3. Schiller HB, et al. 2009. Mol Biol Cell 20:745-56.
4. Leksa V, et al. 2011. Circ Res 108:676-85.
5. Leksa V, et al. 2002. J Biol Chem 277:40575-82.

For research use only. Not intended for use in diagnostic procedures.