The antibody MEM-148 recognizes an extracellular epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.

PRODUCT DETAILS

Clone: MEM-148

Specificity: CD18

Reactivity: Human

Format: Purified

Isotype: Mouse IgG1

Application: FC, IP, WB

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Recommended dilution: 1-5 μg/ml. The antibody MEM-148 is an excellent marker of activated myeloid cells.
Western blotting: Recommended dilution: 1-2 μg/ml.

REFERENCES

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For research use only. Not intended for use in diagnostic procedures.