{"product_id":"pe-dazzle-594-anti-mouse-il-13-w17010b","title":"PE\/Dazzle™ 594 anti-mouse IL-13","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003eMouse IL-13 was initially cloned from cDNA libraries of activated T cells and was designated as P600. IL-13 is an immunoregulatory cytokine secreted predominantly by activated Th2 cells, and it is a key mediator in the pathogenesis of allergic inflammation. IL-13 shares many functional properties with IL-4, and they share a common receptor subunit, the alpha subunit of the IL-4 receptor (IL-4Ra). IL-13 mediates its effects by interacting with a complex receptor system comprised of IL-4Ra and two IL-13 binding proteins, IL-13Ralpha1 and IL-13Ralpha2. Ligation of the IL-13 receptor complex results in signaling via the insulin receptor substrate (IRS)-1 and 2 and STAT-6 pathways. IL-13 has been implicated in inflammatory responses, such as airway hypersensitivity and mucus hypersecretion, inflammatory bowel disease, and parasitic nematode expulsion.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e W17010B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Mouse, Human, Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e IL-13\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG1, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e ICFC - Quality tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/pe-dazzle-594-anti-mouse-il-13-24702+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"25 μg","offer_id":43210638131236,"sku":"159411","price":139.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":43210638164004,"sku":"159412","price":336.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/pe-dazzle-594-anti-mouse-il-13-24702_0.png?v=1769481714","url":"https:\/\/cytekbio.com\/products\/pe-dazzle-594-anti-mouse-il-13-w17010b","provider":"Cytek Biosciences","version":"1.0","type":"link"}