{"product_id":"pe-anti-mouse-human-tox-w17072a","title":"PE anti-mouse\/human TOX","description":"\u003cp\u003eTOX, a member of the high-mobility group (HMG) box superfamily of DNA-binding proteins, was originally identified as a thymic transcript expressed in CD4+CD8+double-positive T cells. Along with TOX2, TOX3, and TOX4, TOX is also part of a small subfamily of transcription factors that share conserved HMG-box sequences. TOX is highly upregulated in thymocytes undergoing positive selection and is required for the differentiation and development of various T cell subsets, including CD4+T cells, regulatory T cells, and natural killer T cells (NKTs). TOX-deficient mice fail to develop lymph nodes and have significantly diminished numbers of CD4+T, NK, and ILC cells.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e W17072A\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Mouse, Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e TOX\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG1, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e ICFC - Quality tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/pe-anti-mouse-human-tox-w17072a-27716+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"25 µg","offer_id":51193959743524,"sku":"377122","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":51193959776292,"sku":"377123","price":360.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/cytekbio.com\/products\/pe-anti-mouse-human-tox-w17072a","provider":"Cytek Biosciences","version":"1.0","type":"link"}