{"product_id":"pe-anti-human-cd46-mem-258","title":"PE Anti-Human CD46 (MEM-258)","description":"\u003cp\u003eThe antibody MEM-258 recognizes an extracellular epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 kDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: MEM-258\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD46\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, Bovine\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: PE\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_198\/R8-93623+Rev.+A_TDS_PE+Anti-Human+CD46+(MEM-258).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry:  The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eOkada N, et al. 1995. Proc Natl Acad Sci U S A 92:2489-93.\u003c\/li\u003e\n\u003cli\u003eMarie JC, et al. 2002. Nat Immunol 3:659-66.\u003c\/li\u003e\n\u003cli\u003eGaggar A, et al. 2003. Nat Med 9:1408-12.\u003c\/li\u003e\n\u003cli\u003eLiszewski MK, et al. 2005. Springer Semin Immunopathol 27:345-58.\u003c\/li\u003e\n\u003cli\u003eOliaro J, et al. 2006. Proc Natl Acad Sci U S A 103:18685-90.\u003c\/li\u003e\n\u003cli\u003eKälin S, et al. 2010. J Virol 84:5336-50.\u003c\/li\u003e\n\u003cli\u003eRebetz J, et al. 2009. PLoS One 4:e8484.\u003c\/li\u003e\n\u003cli\u003eWang H, et al. 2009. Virology 387:436-41.\u003c\/li\u003e\n\u003cli\u003eHoffmann D, et al. 2008. J Invest Dermatol 128:988-98.\u003c\/li\u003e\n\u003cli\u003eFleischli C, et al. 2007. J Gen Virol 88:2925-2934.\u003c\/li\u003e\n\u003cli\u003eLoré K, et al. 2007. J Immunol 179:1721-9.\u003c\/li\u003e\n\u003cli\u003eFremeaux-Bacchi V, et al. 2006. J Am Soc Nephrol 17:2017-25.\u003c\/li\u003e\n\u003cli\u003eWeyand NJ, et al. 2006. Infect Immun 74:2428-35.\u003c\/li\u003e\n\u003cli\u003eFleischli C, et al. 2005. J Virol 79:10013-22.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":52121300107300,"sku":"R7-93623","price":292.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-93623_FC_Profile.png?v=1790388785","url":"https:\/\/cytekbio.com\/products\/pe-anti-human-cd46-mem-258","provider":"Cytek Biosciences","version":"1.0","type":"link"}