{"product_id":"fitc-anti-mouse-mhc-class-ii-i-a-i-e-m5-114","title":"FITC Anti-Mouse MHC Class II (I-A\/I-E) (M5\/114)","description":"\u003cp\u003eThe rat monoclonal antibody M5\/114 reacts with murine MHC class II glycoproteins. It recognizes a shared extracellular determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: M5\/114\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: MHC Class II (I-A\/I-E)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: FITC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Rat IgG2b\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-93247+Rev.+A_TDS_FITC+Anti-Mouse+MHC+Class+II+(I-AI-E)+(M5114).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: The suggested use of this reagent is 2-5 μg\/ml. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eClausen BE, et al. 1998. Immunity 8:143-55.\u003c\/li\u003e\n\u003cli\u003eZang W, et al. 2005. J Am Soc Nephrol 16:3661-8.\u003c\/li\u003e\n\u003cli\u003eKuwano Y, et al. 2007. Int Immunol 19:977-92.\u003c\/li\u003e\n\u003cli\u003eBeers C, et al. 2005. J Immunol 174:1205-12.\u003c\/li\u003e\n\u003cli\u003eKleijmeer M, et al. 2001. J Cell Biol 155:53-63.\u003c\/li\u003e\n\u003cli\u003eDe Souza Leao S, et al. 1995. J Cell Sci 108 ( Pt 10):3219-31.\u003c\/li\u003e\n\u003cli\u003eViville S, et al. 1993. Cell 72:635-48.\u003c\/li\u003e\n\u003cli\u003eBhattacharya A, et al. 1981. J Immunol 127:2488-95.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679817236516,"sku":"R7-93247","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/Symbol_Full_Color_-_JPG_RGB.jpg?v=1613537357","url":"https:\/\/cytekbio.com\/products\/fitc-anti-mouse-mhc-class-ii-i-a-i-e-m5-114","provider":"Cytek Biosciences","version":"1.0","type":"link"}