{"product_id":"fitc-anti-human-cd16-3g8","title":"FITC Anti-Human CD16 (3G8)","description":"\u003cp\u003eThe mouse monoclonal antibody clone 3G8 binds to human IgG receptor III (FcγRIII) that are in two forms: CD16a (FcγRIIIA) and CD16b (FcγRIIIB). With 95% sequence similarity, they are a conventional 50-65 kDa polypeptide-anchored transmembrane protein and a 48 kDa GPI-anchored protein, respectively. CD16a is expressed on NK cells and macrophages, while CD16b is expressed on neutrophils. CD16a also plays a crucial role in antibody-dependent cellular cytotoxicity (ADCC) by NK cells.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: 3G8\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD16\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, Baboon, Capuchin Monkey, Chimpanzee, Common Marmoset, Cynomolgus Monkey, Pigtail Monkey, Rhesus Macaque, Sooty Mangabey, Squirrel Monkey\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: FITC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_198\/R8-93263+Rev.+A_TDS_FITC+Anti-Human+CD16+(3G8).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry:  The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\u003cli\u003ePaul WE. 2003. Fundamental Immunology. Lippincott Williams \u0026amp; Wilkins. Philadelphia PA.\u003c\/li\u003e\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":52121302368292,"sku":"R7-93263","price":239.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-93263_FC_Profile.png?v=1790388830","url":"https:\/\/cytekbio.com\/products\/fitc-anti-human-cd16-3g8","provider":"Cytek Biosciences","version":"1.0","type":"link"}