cFluor® V420 Anti-Human CD3 (SK7)
The SK7 monoclonal antibody binds to human epsilon chain of the CD3 antigen/T-cell antigen receptor, a 20 to 30-kDa protein complex. This complex contains a CD3γ, a CD3δ, a CD3ζ (CD247), two CD3ε, and a T-cell receptor (αβ or γδ) heterodimer1. CD3 is found on all mature T cells, NK T cells and thymocytes. It play a role in recognizing antigen, activating cytotoxic T cell and T helper cell, and signal transduction2. The antibody was conjugated to a fluorophore and puriﬁed by afﬁnity chromatography.
Reactivity: Human, Chimpanzee
Format: cFluor® V420
Isotype: Mouse IgG1, κ
Tested Dilution: 5 μL / test
Application: Flow Cytometry
Storage: 2-8°C and protected from Light. Do not freeze
Formulation: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA).
- Dong, D., et al. 1981. Nature. 573, 546–552
- Weiss A, et al. 1991. Semin Immunol. (5):313-24
This product is intended for in vitro diagnostic use to identify human cells expressing CD3 antigen molecules in countries where the regulatory approval has been obtained from the local regulatory authorities.