{"product_id":"cfluor-byg781-anti-human-cd79a-hm47","title":"cFluor\u003csup\u003e\u0026reg;\u003c\/sup\u003e BYG781 Anti-Human CD79a (HM47)","description":"\u003cp\u003eThe mouse monoclonal antibody clone HM47 binds to human CD79a, an intracellular component of the B-cell receptor (BCR) complex. CD79a (also known as mb-1 or Igα) is a 47 kDa type I transmembrane signaling molecule expressed in the cytoplasm and membrane of B-lineage cells from the earliest recognizable B-cell precursors through mature B cells, and is retained in most B-cell neoplasms. CD79a forms a heterodimer with CD79b to mediate surface immunoglobulin (sIg) transport and signal transduction via ITAM-dependent pathways. Clone HM47 recognizes an intracellular epitope of CD79a and is suitable for flow cytometry following appropriate fixation\/permeabilization.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: HM47\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD79a\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: cFluor\u003csup\u003e®\u003c\/sup\u003e BYG781\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: Flow Cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light. \u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/R8-51529+Rev.+A_TDS_cFluor+BYG781+Anti-Human+CD79a+(HM47).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003cbr\u003e\u003cbr\u003ePlease briefly centrifuge the reagent vial before use.\u003cbr\u003e\u003cbr\u003eUse appropriate personal protective equipment per the product safety data sheet when using this product.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eMason DY, Cordell JL, Brown MH, et al. 1995. J Pathol. 175:151–160.\u003c\/li\u003e\n\u003cli\u003evan Dongen JJM, Lhermitte L, Böttcher S, et al. 2012. Cytometry A. 81A:614–636.\u003c\/li\u003e\n\u003cli\u003eBene MC, Nebe T, Bettelheim P, et al. 1995. Leukemia. 9:1783–1786.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003ecFluor\u003csup\u003e®\u003c\/sup\u003e BYG781 is a tandem dye made with R-PE. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.\u003c\/p\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":43582719885348,"sku":"R7-21529","price":553.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests","offer_id":43582719918116,"sku":"R7-21530","price":222.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/CD79a_HM47_BYG781_x_CD79a_HM47_BYG781_Isotype_Control_combined_a859c431-3237-4de4-9076-4f16dbe6f559.png?v=1771873351","url":"https:\/\/cytekbio.com\/products\/cfluor-byg781-anti-human-cd79a-hm47","provider":"Cytek Biosciences","version":"1.0","type":"link"}