{"product_id":"cfluor-byg575-anti-human-cd58-mem-63","title":"cFluor\u003csup\u003e\u0026reg;\u003c\/sup\u003e BYG575 Anti-Human CD58 (MEM-63)","description":"\u003cp\u003eThe mouse monoclonal antibody clone MEM-63 binds to CD58, a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily, also known as lymphocyte function-associated antigen 3 (LFA-3). Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on both antigen presenting cells and target cells enhances T cell recognition via the interaction with CD2 on the T cell surface.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: MEM-63\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD58\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: cFluor\u003csup\u003e®\u003c\/sup\u003e BYG575\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: Flow Cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light. \u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/R8-51321+Rev.+A_TDS_cFluor+BYG575+Anti-Human+CD58+(MEM-63).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003cbr\u003e\u003cbr\u003ePlease briefly centrifuge the reagent vial before use.\u003cbr\u003e\u003cbr\u003eUse appropriate personal protective equipment per the product safety data sheet when using this product.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eSpringer TA, et al. 1987. Annu. Rev. Immunol. 5:223-252.\u003c\/li\u003e\n\u003cli\u003eDustin ML, et al. 1987. Nature 329:846-848.\u003c\/li\u003e\n\u003cli\u003eArulanandam AR, et al. 1994. J. Exp. Med. 180:1861-1871.\u003c\/li\u003e\n\u003cli\u003eSanders ME, et al. 1988. J. Immunol. 140:1401-1407.\u003c\/li\u003e\n\u003cli\u003eSong S, et al. 2021. Frontiers in Immunology. 12: Article 705140.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":50924851920932,"sku":"R7-21321","price":447.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests","offer_id":50924851953700,"sku":"R7-21322","price":206.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/CD58_MEM-63_BYG575_Side_Scatter_x_CD58_MEM-63_BYG575_Side_Scatter_Isotype_Control_combined.png?v=1781638394","url":"https:\/\/cytekbio.com\/products\/cfluor-byg575-anti-human-cd58-mem-63","provider":"Cytek Biosciences","version":"1.0","type":"link"}