{"product_id":"cellular-senescence-kit-red","title":"Cellular Senescence Kit Red","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003eCellular senescence is a state of stable cell cycle arrest under which cells remain metabolically active, but no longer divide and do not respond to growth-promoting stimuli. It is triggered by a variety of cellular stressors, including environmental factors like ionizing radiation or exposure to chemotherapeutic drugs, oxidative stress, DNA damage, mitochondrial dysfunction, and oncogene activation. Senescence-Associated β-galactosidase (SA-β-gal), a result of altered lysosomal activity, is a hallmark of cellular senescence. Cellular Senescence Kit Red uses a fluorogenic beta-Gal substrate that readily enters into live cells, where it gets cleaved by SA-β-gal inside cells, generating strong red fluorescence. It provides higher sensitivity compared to X-gal staining, a colorimetric method widely available and used to detect Senescence-associated beta-galactosidase (SA-beta-gal) in senescent cells.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Mouse, Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e FC - Quality tested Live cell imaging - Verified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/cellular-senescence-kit-red-24709+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"100 Tests","offer_id":43210666180644,"sku":"421934","price":690.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/cellular-senescence-kit-red-24709_0.png?v=1769481840","url":"https:\/\/cytekbio.com\/products\/cellular-senescence-kit-red","provider":"Cytek Biosciences","version":"1.0","type":"link"}