{"product_id":"biotin-anti-human-cd7-124-1d1","title":"Biotin Anti-Human CD7 (124-1D1)","description":"\u003cp\u003eThe mouse monoclonal antibody clone 124-1D1 binds to human CD7, also known as gp40 or Leu-9. CD7 is a 40 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is highly expressed on thymocytes and mature T cells and is also present on natural killer (NK) cells, hematopoietic progenitor cells, and a minor subset of monocytes. CD7 functions primarily as a costimulatory receptor. Engagement of CD7—including interaction with its characterized ligand SECTM1\/K12—can enhance T-cell activation and proliferation and support NK-cell interferon-gamma secretion. CD7-mediated signaling involves PI3K-associated intracellular pathways. Clone 124-1D1 specifically recognizes human CD7 and is suitable for the identification and analysis of CD7-expressing lymphoid populations in flow cytometry and related immunoassays.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: 124-1D1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Biotin\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-92741+Rev.+A_TDS_Biotin+Anti-Human+CD7+(124-1D1).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: Recommended dilution: 1-5 μg\/ml.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003evan Dongen JJM, Lhermitte L, Böttcher S, et al. 2012. Cytometry A. 81A: 614–636.\u003c\/li\u003e\n\u003cli\u003eBene MC, Nebe T, Bettelheim P, et al. 1995. Leukemia. 9(10):1783–1786.\u003c\/li\u003e\n\u003cli\u003eOrfao A, Schmitz G, Brando B, et al. 1999. Clin Chem Lab Med. 37(11–12):983–990.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679804620836,"sku":"R7-92741","price":239.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-92741_FC_Profile.png?v=1792020052","url":"https:\/\/cytekbio.com\/products\/biotin-anti-human-cd7-124-1d1","provider":"Cytek Biosciences","version":"1.0","type":"link"}