{"product_id":"biotin-anti-human-cd16-mem-154","title":"Biotin Anti-Human CD16 (MEM-154)","description":"\u003cp\u003eThe antibody MEM-154 reacts with an extracellular epitope on CD16 antigen that is residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgammaRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes, and it can be used for mapping CD16-158V\/F polymorphism on NK cells, as it requires presence of V at amino acid 158.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: MEM-154\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD16\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Biotin\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC, IP\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-92763+Rev.+A_TDS_Biotin+Anti-Human+CD16+(MEM-154).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: Recommended dilution: 5-8 μg\/ml;  positive control: PBL (peripheral blood lymphocytes). The antibody MEM-154 does not react with CD16a present on NK cells in many subjects.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eGessner JE, et al. 1995. J Biol Chem 270:1350-61.\u003c\/li\u003e\n\u003cli\u003eKocher M, et al. 1997. J Immunol 159:3940-8.\u003c\/li\u003e\n\u003cli\u003eArase N, et al. 2003. J Immunol 170:3054-8.\u003c\/li\u003e\n\u003cli\u003eGasdaska JR, et al. 2012. Mol Immunol 50:134-41.\u003c\/li\u003e\n\u003cli\u003eOhradanova-Repic A, et al. 2018. Front Immunol 9:852.\u003c\/li\u003e\n\u003cli\u003eTamm A, et al. 1996. J Immunol 157:1576-81.\u003c\/li\u003e\n\u003cli\u003ede Haas M, et al. 1996. J Immunol 156:2948-55.\u003c\/li\u003e\n\u003cli\u003eKoene HR, et al. 1997. Blood 90:1109-14.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679802523684,"sku":"R7-92763","price":239.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-92763_FC_Profile.png?v=1792019994","url":"https:\/\/cytekbio.com\/products\/biotin-anti-human-cd16-mem-154","provider":"Cytek Biosciences","version":"1.0","type":"link"}