{"product_id":"apc-anti-mouse-il-21-s20017b","title":"APC anti-mouse IL-21","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003eInterleukin 21 (IL-21) is a potent immunomodulatory cytokine primarily produced by NKT cells and CD4+ T cells, particularly the inflammatory Th17 subset. It exerts pleiotropic effects on both innate and adaptive immune responses. These include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. IL-21 also has proapoptotic effects on B cells and NK cells. Recent studies have shown that IL-21 functions as an autocrine cytokine, strongly inducing Th17 differentiation and suppressing Foxp3 expression, making it a potential therapeutic target for treating cancer and inflammatory diseases.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e S20017B\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e IL-21\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG1, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e ICFC - Quality tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/apc-anti-mouse-il-21-25397+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"25 μg","offer_id":43210696785956,"sku":"122203","price":165.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":43210696818724,"sku":"122204","price":340.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/apc-anti-mouse-il-21-25397_0.png?v=1769482014","url":"https:\/\/cytekbio.com\/products\/apc-anti-mouse-il-21-s20017b","provider":"Cytek Biosciences","version":"1.0","type":"link"}