{"product_id":"alexa-fluor-647-anti-sp1-w21043e","title":"Alexa Fluor® 647 anti-SP1","description":"\u003cp\u003eSP1 belongs to the transcription factor SP\/KLF family, which contains three zinc finger domains that can bind to GC boxes and regulate transcription of a variety of molecules. SP1 regulates efferent gene transcription positively and negatively, participating broadly in cellular development and physiological functions as a generally expressed transcription factor. Post-translational modifications, including phosphorylation, glycosylation, acetylation, ubiquitylation, and SUMOylation, highly regulate SP1’s function and stability. SP1 is required to develop and differentiate early embryo, placenta, and sperm cells. SP1 is highly expressed in multiple cancers including breast, stomach, pancreas, lung, and brain. SP1 promotes tumor cell proliferation, inactivates cell death, and facilitates immune escape.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e W21043E\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e SP1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Rat\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG2a, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e IHC-P - Quality tested ICC - Verified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/alexa-fluor-647-anti-sp1-w21043e-28199+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"25 μg","offer_id":51193990971428,"sku":"615253","price":190.0,"currency_code":"USD","in_stock":true},{"title":"100 μg","offer_id":51193991004196,"sku":"615254","price":495.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/cytekbio.com\/products\/alexa-fluor-647-anti-sp1-w21043e","provider":"Cytek Biosciences","version":"1.0","type":"link"}