{"product_id":"alexa-fluor-647-anti-human-cd64-10-1","title":"Alexa Fluor\u003csup\u003e\u0026trade;\u003c\/sup\u003e 647 Anti-Human CD64 (10.1)","description":"\u003cp\u003eThe mouse monoclonal antibody clone 10.1 binds to human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 functions as a high-affinity receptor for IgG, facilitating antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and cytokine production. CD64 is expressed on monocytes, macrophages, dendritic cells, and activated granulocytes, while mature granulocytes and lymphocytes lack expression. Increased expression of CD64 on neutrophils may be indicative of an active immune response to bacterial infection or sepsis in research applications. The 10.1 clone reportedly blocks the binding of immunoglobulin to FcRI.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: 10.1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD64\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Alexa Fluor™ 647\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-94465+Rev.+A_TDS_Alexa+Fluor+647+Anti-Human+CD64+(10.1).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry:  The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e“Alexa Fluor“ is a trademark of Thermo Fisher Scientific Inc.","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":67679265423396,"sku":"R7-94465","price":292.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-94465_FC_Profile.png?v=1792019587","url":"https:\/\/cytekbio.com\/products\/alexa-fluor-647-anti-human-cd64-10-1","provider":"Cytek Biosciences","version":"1.0","type":"link"}