{"product_id":"purified-anti-human-pag1-mem-255","title":"Purified Anti-Human PAG1 (MEM-255)","description":"\u003cp\u003eThe antibody MEM-255 recognizes an epitope (aa 235-280) of Csk-binding protein (Cbp) located in the cytoplasmic domain, also known as protein associated with glycosphingolipid-enriched microdomains (PAG).\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: MEM-255\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: PAG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG2a\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: WB, IHC-P, FC-IC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-91373+Rev.+A_TDS_Purified+Anti-Human+PAG1+(MEM-255).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: Recommended dilution: 2 μg\/ml. Intracellular staining.\u003cbr\u003eImmunohistochemistry (paraffin sections): Positive tissue: tonsil, spleen. \u003cbr\u003eWestern blotting: Csk binding protein is an ubiquitously expressed 46 kDa transmembrane adaptor protein present in membrane microdomains (rafts), which, however, migrates on SDS-PAGE gels anomalously as an 80 kDa molecule.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eSemac I, et al. 2003. Cancer Res 63:534-40.\u003c\/li\u003e\n\u003cli\u003eBrdicka T, et al. 2000. J Exp Med 191:1591-604.\u003c\/li\u003e\n\u003cli\u003eBrdicková N, et al. 2001. FEBS Lett 507:133-6.\u003c\/li\u003e\n\u003cli\u003eSchatzlmaier P, et al. 2015. Sci Signal 8:rs11.\u003c\/li\u003e\n\u003cli\u003eTedoldi S, et al. 2006. Blood 107:213-21.\u003c\/li\u003e\n\u003cli\u003eDavidson D, et al. 2003. Mol Cell Biol 23:2017-28.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679923142692,"sku":"R7-91373","price":239.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-91373_FC_Histogram.png?v=1792021548","url":"https:\/\/cytekbio.com\/ja\/products\/purified-anti-human-pag1-mem-255","provider":"Cytek Biosciences","version":"1.0","type":"link"}