{"product_id":"purified-anti-human-lox-1-15c4","title":"Purified Anti-Human LOX-1 (15C4)","description":"\u003cp\u003eThe mouse monoclonal antibody clone 15C4 binds to the human lectin-like oxidized LDL receptor 1 (LOX-1), also known as CLEC8A. LOX-1 is a 31 kDa single-pass type II transmembrane protein and a member of the C-type lectin superfamily. It is a scavenger receptor that is involved in endocytosis, phagocytosis, and cytokine production. LOX-1 is expressed by endothelial cells, smooth muscle cells, platelets, fibroblasts, and macrophages, and is upregulated by inflammatory and oxidative stimuli. LOX-1 recognizes numerous ligands, including lipoproteins, apoptotic cells, heat shock proteins, C-reactive protein, and oxidized LDL.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: 15C4\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: LOX-1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG2a, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: ICC, FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-92165+Rev.+A_TDS_Purified+Anti-Human+LOX-1+(15C4).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: Recommended dilution: 1-5 µg\/ml\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eLi D, et al. 2012. J Exp Med. 209:109-121.\u003c\/li\u003e\n\u003cli\u003eJoo, H., et. al. 2014. Immunity. 41:592-604.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679909871652,"sku":"R7-92165","price":186.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-92165_FC_Profile.png?v=1792021438","url":"https:\/\/cytekbio.com\/ja\/products\/purified-anti-human-lox-1-15c4","provider":"Cytek Biosciences","version":"1.0","type":"link"}