{"product_id":"purified-anti-human-cd18-mem-148","title":"Purified Anti-Human CD18 (MEM-148)","description":"\u003cp\u003eThe antibody MEM-148 recognizes an extracellular epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: MEM-148\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD18\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: Purified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC, IP, WB\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-91359+Rev.+A_TDS_Purified+Anti-Human+CD18+(MEM-148).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry: Recommended dilution: 1-5 μg\/ml. The antibody MEM-148 is an excellent marker of activated myeloid cells. \u003cbr\u003eWestern blotting: Recommended dilution: 1-2 μg\/ml.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eDassanayake RP, et al. 2007. Infect Immun 75:5004-10.\u003c\/li\u003e\n\u003cli\u003ePeters T, et al. 2006. J Investig Dermatol Symp Proc 11:7-15.\u003c\/li\u003e\n\u003cli\u003eSolovjov DA, et al. 2005. J Biol Chem 280:1336-45.\u003c\/li\u003e\n\u003cli\u003eKess D, et al. 2003. J Immunol 171:5697-706.\u003c\/li\u003e\n\u003cli\u003eShang XZ, et al. 1998. Eur J Immunol 28:1970-9.\u003c\/li\u003e\n\u003cli\u003eDrbal K, et al. 2000. Biochem Biophys Res Commun 275:295-9.\u003c\/li\u003e\n\u003cli\u003eGao JX, et al. 1996. Immunology 88:463-70.\u003c\/li\u003e\n\u003cli\u003eOsicka R, et al. 2015. Elife 4:e10766.\u003c\/li\u003e\n\u003cli\u003eMachacek C, et al. 2016. J Immunol 197:2229-38.\u003c\/li\u003e\n\u003cli\u003eDrbal K, et al. 2000. Biochem Biophys Res Commun 275:295-9.\u003c\/li\u003e\n\u003cli\u003eDrbal K, et al. 2001. Immunobiology 203:687-98.\u003c\/li\u003e\n\u003cli\u003eAubert M, et al. 2009. J Virol 83:6171-83.\u003c\/li\u003e\n\u003cli\u003eDrbal K, et al. 2001. Blood 98:1561-6.\u003c\/li\u003e\n\u003cli\u003eKanderova V, et al. 2016. Mol Cell Proteomics 15:1246-61.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 µg","offer_id":67679886442532,"sku":"R7-91359","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-91359_FC_Profile.png?v=1792021076","url":"https:\/\/cytekbio.com\/ja\/products\/purified-anti-human-cd18-mem-148","provider":"Cytek Biosciences","version":"1.0","type":"link"}