{"product_id":"phagocytosis-detection-kit-red","title":"Phagocytosis Detection Kit Red","description":"\u003cp\u003e\u003c\/p\u003e\u003cp\u003ePhagocytosis is a complex process for the ingestion and elimination of pathogens. It is also important for the elimination of apoptotic cells, hence fundamental for tissue homeostasis. Phagocytosis consists of recognition and ingestion of particles larger than 0.5 µm into a plasma membrane-derived vesicle, known as phagosome. Professional phagocytes include monocytes, macrophages, neutrophils, dendritic cells, osteoclasts, and eosinophils. These cells are in charge of eliminating microorganisms and presenting them to cells of the adaptive immune system. In addition, fibroblasts, epithelial cells, and endothelial cells can also perform phagocytosis. These nonprofessional phagocytes cannot ingest microorganisms but are important in eliminating apoptotic bodies. Once internalized, the phagosome fuse with lysosomes to form secondary phagolysosomes for digestion, resulting in progressive decrease of pH. Streamline your phagocytosis research with BioLegend’s Phagocytosis Detection Kit Red. This ready-to-use fluorimetric assay kit is designed for analysis of phagocytic activity in live cells. This kit provides a simple, sensitive method to monitor cellular uptake using pH-activated Phagocytosis Detection Beads. These latex beads are conjugated to a red dye which is non-fluorescent at neutral pH but dramatically increases fluorescence upon internalization into acidic phagosomes. This kit also includes Viability Dye Green enabling simultaneous measurement of cellular uptake and cell viability in a single assay. This dual-color approach provides critical context by distinguishing between reduced phagocytosis due to cellular dysfunction versus specific inhibition of the phagocytic process.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e None\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e Live cell imaging - Quality tested FC - Verified\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/phagocytosis-detection-kit-red-25591+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"1 kit","offer_id":43210608115748,"sku":"421938","price":405.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/phagocytosis-detection-kit-red-25591_0.png?v=1769481596","url":"https:\/\/cytekbio.com\/ja\/products\/phagocytosis-detection-kit-red","provider":"Cytek Biosciences","version":"1.0","type":"link"}