{"product_id":"pe-fire-744-anti-mouse-human-klrg1-mafa-2f1-klrg1","title":"PE\/Fire™ 744 anti-mouse\/human KLRG1 (MAFA)","description":"\u003cp\u003eKiller cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).  KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.  It is composed of a homodimer of glycosylated 30-38 kD subunits.  Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.  KLRG1 is also expressed on subsets of CD8+and CD4+cells, including CD4+and CD8+effector\/memory cells, potent regulatory CD4+T cells.  KLRG1 may be involved in regulating NK cell homeostasis.  KLRG1 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e 2F1\/KLRG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Mouse, Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e KLRG1\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Syrian Hamster\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e FC - Quality tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/pe-fire-744-anti-mouse-human-klrg1-mafa-2f1-klrg1-27507+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"100 µg","offer_id":51193946210340,"sku":"138446","price":449.0,"currency_code":"USD","in_stock":true},{"title":"25 µg","offer_id":51193946243108,"sku":"138445","price":216.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/pe-fire-744-anti-mouse-human-klrg1-mafa-2f1-klrg1-27507_0.png?v=1785435012","url":"https:\/\/cytekbio.com\/ja\/products\/pe-fire-744-anti-mouse-human-klrg1-mafa-2f1-klrg1","provider":"Cytek Biosciences","version":"1.0","type":"link"}