{"product_id":"fitc-anti-human-cd279-pd-1-eh12-2h7","title":"FITC Anti-Human CD279 (PD-1) (EH12.2H7)","description":"\u003cp\u003eThe mouse monoclonal antibody clone EH12.2H7 binds to human CD279 (PD-1), an inhibitory checkpoint receptor expressed on activated T cells, B cells, NK cells, and subsets of myeloid cells. CD279 plays a central role in immune exhaustion, tolerance, and suppression during chronic antigen exposure and malignancy. Clone EH12.2H7 binds an extracellular epitope and is suited for flow cytometric profiling of T-cell exhaustion, immune checkpoint expression, and tumor-infiltrating lymphocyte characterization\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: EH12.2H7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD279 (PD-1)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, African Green Monkey, Baboon, Chimpanzee, Common Marmoset, Cynomolgus Monkey, Rhesus Macaque, Squirrel Monkey, Non-Human Primate\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: FITC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_198\/R8-93025+Rev.+A_TDS_FITC+Anti-Human+CD279+(PD-1)+(EH12.2H7).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry:  The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eDong H, et al. 2002. Nat Med. 8:793–800.\u003c\/li\u003e\n\u003cli\u003eWherry EJ. 2011. Nat Immunol. 12:492–499.\u003c\/li\u003e\n\u003cli\u003eGros A, et al. 2014. J Clin Invest. 124:2246–2259.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":52121303482404,"sku":"R7-93025","price":239.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-93025_FC_Profile.png?v=1790388867","url":"https:\/\/cytekbio.com\/ja\/products\/fitc-anti-human-cd279-pd-1-eh12-2h7","provider":"Cytek Biosciences","version":"1.0","type":"link"}