{"product_id":"cfluor-byg667-anti-human-cd10-hi10a","title":"cFluor\u003csup\u003e\u0026reg;\u003c\/sup\u003e BYG667 Anti-Human CD10 (HI10a)","description":"\u003cp\u003eThe mouse monoclonal antibody clone HI10a binds to human CD10, a 100 kDa neutral endopeptidase that is a member of the metalloprotease family. CD10 is also known as the common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. In normal cells, CD10 is expressed on early B and T lymphoid precursors, neutrophils, and various epithelia. CD10 is also expressed on several lymphoma cells, including Burkitt’s, acute lymphoblastic, and follicular germinal center lymphomas. CD10 functions as an endopeptidase, is involved in B cell development, and is a mediator of neutrophil inflammatory responses. CD10 is also recognized as a biomarker for hematopoietic and tissue stem cells, with recent studies suggesting its expression may have prognostic significance in leukemia and solid tumors.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: HI10a\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: cFluor\u003csup\u003e®\u003c\/sup\u003e BYG667\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: Flow Cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light. \u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/R8-51571+Rev.+A_TDS_cFluor+BYG667+Anti-Human+CD10+(HI10a).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003cbr\u003e\u003cbr\u003ePlease briefly centrifuge the reagent vial before use.\u003cbr\u003e\u003cbr\u003eUse appropriate personal protective equipment per the product safety data sheet when using this product.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eLetarte M, Vera S, et al. J Exp Med. 1988;168(3):1247-1253.\u003c\/li\u003e\n\u003cli\u003evan Dongen JJM, Lhermitte L, Böttcher S, et al. Leukemia. 2012; 26(9):1908–1975.\u003c\/li\u003e\n\u003cli\u003eShipp MA, Look AT. Blood. 1993; 82(4):1052–1070.\u003c\/li\u003e\n\u003cli\u003eLeBien TW, McCormack RT, et al. Blood. 1989;73(3):625-635.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003ecFluor\u003csup\u003e®\u003c\/sup\u003e BYG667 is a tandem dye made with R-PE. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.\u003c\/p\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":50924851527716,"sku":"R7-21571","price":400.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests","offer_id":50924851560484,"sku":"R7-21572","price":197.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/CD10_HI10a_BYG667.png?v=1781638386","url":"https:\/\/cytekbio.com\/ja\/products\/cfluor-byg667-anti-human-cd10-hi10a","provider":"Cytek Biosciences","version":"1.0","type":"link"}