{"product_id":"cfluor-byg575-anti-human-cd279-pd-1-eh12-2h7","title":"cFluor\u003csup\u003e\u0026reg;\u003c\/sup\u003e BYG575 Anti-Human CD279 (PD-1) (EH12.2H7)","description":"\u003cp\u003eThe mouse monoclonal antibody clone EH12.2H7 binds to human CD279 (PD-1), an inhibitory checkpoint receptor expressed on activated T cells, B cells, NK cells, and subsets of myeloid cells. CD279 plays a central role in immune exhaustion, tolerance, and suppression during chronic antigen exposure and malignancy. Clone EH12.2H7 binds an extracellular epitope and is suited for flow cytometric profiling of T-cell exhaustion, immune checkpoint expression, and tumor-infiltrating lymphocyte characterization\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: EH12.2H7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD279 (PD-1)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, African Green Monkey, Baboon, Chimpanzee, Common Marmoset, Cynomolgus Monkey, Rhesus Macaque, Squirrel Monkey, Non-Human Primate\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: cFluor\u003csup\u003e®\u003c\/sup\u003e BYG575\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: Flow Cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light. \u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/R8-51549+Rev.+A_TDS_cFluor+BYG575+Anti-Human+CD279+(PD-1)+(EH12.2H7).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003cbr\u003e\u003cbr\u003ePlease briefly centrifuge the reagent vial before use.\u003cbr\u003e\u003cbr\u003eUse appropriate personal protective equipment per the product safety data sheet when using this product.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eDong H, et al. 2002. Nat Med. 8:793–800.\u003c\/li\u003e\n\u003cli\u003eWherry EJ. 2011. Nat Immunol. 12:492–499.\u003c\/li\u003e\n\u003cli\u003eGros A, et al. 2014. J Clin Invest. 124:2246–2259.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":44228302143524,"sku":"R7-21549","price":325.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests","offer_id":44228302176292,"sku":"R7-21550","price":175.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/PD-1_BYG575_x_Mouse_IgG1_BYG575_combined.png?v=1780511041","url":"https:\/\/cytekbio.com\/ja\/products\/cfluor-byg575-anti-human-cd279-pd-1-eh12-2h7","provider":"Cytek Biosciences","version":"1.0","type":"link"}