{"product_id":"cfluor-b515-anti-human-mouse-cd11b-m1-70","title":"cFluor\u003csup\u003e\u0026reg;\u003c\/sup\u003e B515 Anti-Human\/Mouse CD11b (M1\/70)","description":"\u003cp\u003eThe rat monoclonal antibody clone M1\/70 binds to human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin α-receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g., fibrinogen (cell-matrix). In addition, integrin α's are active signaling receptors that recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin α-receptors consist of distinct combinations of integrin α-chains, which are differentially expressed. integrin alpha M (CD11b) assembles with integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1, ICAM-2, ICAM-3, and ICAM-4 on endothelial cells and can also facilitate the removal of iC3b-bearing foreign cells.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: M1\/70\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD11b\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human, Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: cFluor\u003csup\u003e®\u003c\/sup\u003e B515\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Rat IgG2b, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µl\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: Flow Cytometry\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light. \u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/R8-51387+Rev.+A_TDS_cFluor+B515+Anti-Human+Mouse+CD11b+(M170).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eEach lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.\u003cbr\u003e\u003cbr\u003ePlease briefly centrifuge the reagent vial before use.\u003cbr\u003e\u003cbr\u003eUse appropriate personal protective equipment per the product safety data sheet when using this product.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003ecFluor\u003csup\u003e®\u003c\/sup\u003e B515 is equivalent to CF\u003csup\u003e®\u003c\/sup\u003e488A manufactured and provided by Biotium, Inc. under an Agreement between Biotium and Cytek (LICENSEE). The manufacture, use, sale, offer for sale, or import of the product is covered by one or more of the patents or pending applications owned or licensed by Biotium. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser’s own internal research. No right under any other patent claim, no right to perform any patented method, and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppel.\u003c\/p\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":43805889986596,"sku":"R7-21387","price":262.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests","offer_id":43805890019364,"sku":"R7-21388","price":111.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/CD11b_M1-70_B515.png?v=1773438598","url":"https:\/\/cytekbio.com\/ja\/products\/cfluor-b515-anti-human-mouse-cd11b-m1-70","provider":"Cytek Biosciences","version":"1.0","type":"link"}