{"product_id":"brilliant-violet-421-anti-human-cd158z-kir3dl3-s23011e","title":"Brilliant Violet 421™ anti-human CD158z (KIR3DL3)","description":"\u003cp\u003eCD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembrane proteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmic domains contain ITIMs and possess inhibitory functions and others with short cytoplasmic region lack ITIMs and have activation functions. Fifteen polymorphic KIR genes have been reported in humans.CD158z is a glycoprotein with three extracellular Ig domains and a long cytoplasmic tail containing an ITIM motif. It is reportedly expressed on intraepithelial γδ and CD8+ T cells. KIR3DL3 has been reported to bind to HHLA2 (B7H7) to cause downstream functional inhibition.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone:\u003c\/b\u003e S23011E\u003c\/p\u003e\u003cp\u003e\u003cb\u003eAntibody Type:\u003c\/b\u003e Monoclonal\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity:\u003c\/b\u003e Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat:\u003c\/b\u003e CD158z\u003c\/p\u003e\u003cp\u003e\u003cb\u003eHost:\u003c\/b\u003e Mouse\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype:\u003c\/b\u003e IgG2a, κ\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplications:\u003c\/b\u003e FC - Quality tested\u003c\/p\u003e\u003cp\u003e\u003cb\u003eRegulatory Status:\u003c\/b\u003e RUO\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eData Sheets:\u003c\/strong\u003e \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/biolegend\/brilliant-violet-421-anti-human-cd158z-kir3dl3-s23011e-27693+(TDS).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/biolegend\/Pure_Conjugated_Antibodies_SDS_United_States_English_V2.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eNote to Purchaser: \u003c\/strong\u003eThis product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.\u003c\/p\u003e","brand":"BioLegend","offers":[{"title":"25 Tests","offer_id":51193985138724,"sku":"334909","price":193.0,"currency_code":"USD","in_stock":true},{"title":"100 Tests","offer_id":51193985171492,"sku":"334910","price":407.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/brilliant-violet-421-anti-human-cd158z-kir3dl3-s23011e-27693_0.png?v=1785435209","url":"https:\/\/cytekbio.com\/ja\/products\/brilliant-violet-421-anti-human-cd158z-kir3dl3-s23011e","provider":"Cytek Biosciences","version":"1.0","type":"link"}