{"product_id":"apc-cyanine7-anti-human-cd90-5e10","title":"APC-Cyanine7 Anti-Human CD90 (5E10)","description":"\u003cp\u003eThe mouse monoclonal antibody clone 5E10 reacts with human CD90, also known as Thy-1 (thymus cell antigen-1), a 25–37 kDa GPI-anchored glycoprotein and the smallest member of the immunoglobulin superfamily. CD90 contains a single V-type Ig domain and, lacking an intracellular domain, signals through lateral interactions with Src family kinases, G-inhibitory proteins, and RGD-binding integrins within lipid rafts. CD90 is expressed on thymocytes, neurons, fibroblasts, activated endothelial cells, and a small subset of CD3+CD4+ T cells in peripheral blood. In the hematopoietic compartment, CD90 marks a subset of CD34+ prothymocytes and hematopoietic stem cells in bone marrow, fetal liver, and cord blood, where the CD90+CD34+ population is enriched for long-term culture-initiating cells. CD90 is also a defining surface marker of mesenchymal stromal cells (MSCs), included in the minimal criteria established by the International Society for Cell Therapy. CD90 participates in cell-cell and cell-matrix adhesion, T cell signal transduction, neurite outgrowth, and regulation of MSC differentiation capacity. This antibody is reported for use in flow cytometric analysis, immunoprecipitation, western blotting, and immunohistology of frozen tissue sections.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eClone\u003c\/b\u003e: 5.00E+10\u003c\/p\u003e\u003cp\u003e\u003cb\u003eSpecificity\u003c\/b\u003e: CD90\u003c\/p\u003e\u003cp\u003e\u003cb\u003eReactivity\u003c\/b\u003e: Human\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormat\u003c\/b\u003e: APC-Cyanine7\u003c\/p\u003e\u003cp\u003e\u003cb\u003eIsotype\u003c\/b\u003e: Mouse IgG1, k\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTested Dilution\u003c\/b\u003e: 5 µL\/Test\u003c\/p\u003e\u003cp\u003e\u003cb\u003eApplication\u003c\/b\u003e: FC\u003c\/p\u003e\u003cp\u003e\u003cb\u003eStorage\u003c\/b\u003e: 2-8°C protected from light.\u003cb\u003eDo not freeze\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eFormulation\u003c\/b\u003e: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide\u003c\/p\u003e\u003cp\u003e\u003cb\u003eData Sheets: \u003c\/b\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/cfluor\/project_elva_2k\/R8-94977+Rev.+A_TDS_APC-Cyanine7+Anti-Human+CD90+(5E10).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/SDS\/R9-70004+Rev.+E_SDS+fluorescent+conjugated+Abs.pdf\" target=\"_blank\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eRECOMMENDED USAGE\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eFlow cytometry:  The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e\u003col\u003e\n\u003cli\u003eDominici, M. et al. 2006. Cytotherapy 8: 315–317.\u003c\/li\u003e\n\u003cli\u003eRege, T.A. and Hagood, J.S. 2006. Am. J. Respir. Cell Mol. Biol. 34: 646–655. Sauzay, C. et al. 2019. Front. Cell Dev. Biol. 7: 66.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cbr\u003e\u003cp\u003e\u003cstrong\u003eFor research use only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003e\u003cp\u003eAPC-Cyanine7 is a tandem dye made with APC. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.\u003c\/p\u003e","brand":"Cytek Biosciences","offers":[{"title":"100 Tests","offer_id":67679800328228,"sku":"R7-94977","price":332.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/R7-94977_FC_Histogram.png?v=1792019961","url":"https:\/\/cytekbio.com\/ja\/products\/apc-cyanine7-anti-human-cd90-5e10","provider":"Cytek Biosciences","version":"1.0","type":"link"}