{"title":"Tonbo\u003csup\u003e®\u003c\/sup\u003e Reagents","description":"","products":[{"product_id":"ez-brdu-kit","title":"Tonbo® EZ-BrdU™ Kit","description":"\u003cp\u003eSKU :TNB-6600\u003c\/p\u003e\n\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-TNB-6600.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eThe incorporation of BrdU into newly synthesized DNA by actively cycling cells is one method for measuring the changing amount of cellular DNA during cell proliferation through each of the cell cycle phases. As a thymidine analog, BrdU is preferentially incorporated into newly replicated DNA which can then be subsequently labeled and analyzed to determine relative DNA content and cell cycle position. Incorporation of BrdU is most commonly detected using anti-BrdU antibodies.\u003c\/p\u003e\n\u003cp\u003eA BrdU solution is provided for exposure of actively cycling cells to incorporate BrdU. The EZ-BrdU Kit employs an acid denaturation step. The mild acid method used helps reduce damage to other cellular proteins. After the denaturation step, cells are stained with a FITC anti-BrdU antibody and total DNA is counterstained with a PI\/RNase A solution. Two color flow cytometry can then be used to analyze cells that have incorporated BrdU (proliferating cells) in terms of their cell cycle position (G0\/1, S, or G2\/M phase).\u003c\/p\u003e\n\u003cp\u003eThe EZ-BrdU Kit is shipped in one container and consists of two packages plus instruction manual. Upon arrival one should be stored at 2-8°C and the other at -20°C.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eThe EZ-BrdU™ Kit is developed and manufactured for Cytek Biosciences, Inc. by Phoenix Flow Systems, Inc. \"EZ-BrdU\" is a trademark of Phoenix Flow Systems, Inc.\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eEZ-BrdU™ Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eTNB-6600\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePRB-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFITC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCytek SpectroFlo Template Settings\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e\u003ca href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/SpectroFlo%20Templates\/EZ%20BrdU%20Template%203.0.zip\" target=\"_blank\"\u003e SpectroFlo Template and User Settings\u003c\/a\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"Kit","offer_id":40581228855332,"sku":"TNB-6600-KIT","price":428.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/ez_eb584bf8-e4b6-47f8-a0dc-8fcb8f359385.png?v=1675106331"},{"product_id":"mouse-tbnk-myeloid-treg-kit","title":"Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit","description":"\u003cp\u003eThe Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit is designed by Cytek scientists to enable researchers to quicklyperform basic immunophenotyping and analyze B cell, T cell, NK cell, myeloid and regulatory T cell (Treg) populationsin mouse samples. This pre-titered ready-to-use mouse kit contains three sets of reagents that are fully optimized forbest performance on the Cytek Aurora\u003csup\u003e™\u003c\/sup\u003e and Cytek Northern Lights\u003csup\u003e™\u003c\/sup\u003e full spectrum systems.\u003c\/p\u003e\u003cp\u003eThe Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit can also be used as a backbone to expand to a broader panel.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cul\u003e\u003cli\u003e\u003ca rel=\"noopener\" title=\"Cytek Tonbo Mouse TBNK\/Myeloid\/Treg Kit Flyer\" href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/documentation-center\/Brochures\/N9-20090-Tonbo-Mouse-TBNK-Myeloid-Treg-Kit-Flyer.pdf\" target=\"_blank\"\u003eDownload Flyer\u003c\/a\u003e\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eProducts required for the kit but not included:\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003e\u003ca href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\" title=\"Ghost Dye™ Violet 540\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Ghost Dye\u003csup\u003e®\u003c\/sup\u003e Violet 540\u003c\/a\u003e\u003c\/li\u003e \u003cli\u003e\u003ca href=\"https:\/\/cytekbio.com\/products\/foxp3-transcription-factor-staining-buffer-kit\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/foxp3-transcription-factor-staining-buffer-kit\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Foxp3 \/ Transcription Factor Staining Buffer Kit\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTube 1: TBNK Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-1-Tube-1-95-K101.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-1-Tube-1-95-K101.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTable 1: \u003c\/span\u003e\u003c\/strong\u003eComposition of Tube 1: TBNK Identification Tube (P\/N 95-K101) of the Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit (P\/N 95-K001). \u003ca href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\" title=\"Ghost Dye™ Violet 540\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Ghost Dye\u003csup\u003e®\u003c\/sup\u003e Violet 540 (P\/N 13-0879)\u003c\/a\u003e is available to purchase separately.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eTube 2: Myeloid Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-2-Tube-2-95-K201.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-2-Tube-2-95-K201.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTable 2: \u003c\/span\u003e\u003c\/strong\u003eComposition of Tube 2: Myeloid Identification Tube (P\/N 95-K201) of the Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit (P\/N 95-K001). \u003ca href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\" title=\"Ghost Dye™ Violet 540\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Ghost Dye\u003csup\u003e®\u003c\/sup\u003e Violet 540 (P\/N 13-0879)\u003c\/a\u003e is available to purchase separately.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eTube 3: Treg Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-3-Tube-3-95-K301.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Table-3-Tube-3-95-K301.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eTable 3: \u003c\/span\u003e\u003c\/strong\u003eComposition of Tube 3: Treg Identification Tube (P\/N 95-K301) of the Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit (P\/N 95-K001). \u003ca href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\" title=\"Ghost Dye™ Violet 540\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/ghost-dye-violet-540\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Ghost Dye\u003csup\u003e®\u003c\/sup\u003e Violet 540 (P\/N 13-0879)\u003c\/a\u003e and \u003ca href=\"https:\/\/cytekbio.com\/products\/foxp3-transcription-factor-staining-buffer-kit\" target=\"_blank\" data-mce-href=\"https:\/\/cytekbio.com\/products\/foxp3-transcription-factor-staining-buffer-kit\"\u003eCytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Foxp3 \/ Transcription Factor Staining Buffer Kit (P\/N TNB-0607-KIT)\u003c\/a\u003e are available to purchase separately.\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eDATA\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003eTube 1: TBNK Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-1-Data-95-K101.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-1-Data-95-K101.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFigure 1: \u003c\/span\u003e\u003c\/strong\u003eTube 1 enables the identification of lymphocytes, total T cells, helper T cells, cytotoxic T cells, memory and naïve T cells, B cells, and NK cells. Events are first gated on singlets, red blood cell (RBC) exclusion, and viable CD45\u003csup\u003e+\u003c\/sup\u003e cells. The CD45\u003csup\u003e+\u003c\/sup\u003e cells are then divided into CD49b\u003csup\u003e+\u003c\/sup\u003eNK1.1\u003csup\u003e+\u003c\/sup\u003e cells which were further segregated into NK cells and NKT cells by expression of CD3. Within not-NK cells, T cells are characterized by expression of CD3 and separated by TCRß. T cell subsets are further characterized by expression of CD4, CD8, CD44, and CD62L to identify helper, cytotoxic, central memory (CM), effector memory (EM), and naïve T cells. In the CD3\u003csup\u003e-\u003c\/sup\u003e gate, B cells are quantified as B220\u003csup\u003e+\u003c\/sup\u003eCD19\u003csup\u003e+\u003c\/sup\u003e.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eTube 2: Myeloid Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-2-Data-95-K201.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-2-Data-95-K201.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFigure 2: \u003c\/span\u003e\u003c\/strong\u003eTube 2 enables the identification of the myeloid subsets: monocytes, macrophages, and neutrophils, in addition to the dendritic cell subsets: conventional type 1 dendritic cells (cDC1), conventional type 2 dendritic cells (cDC2), and plasmacytoid dendritic cells (pDC). Events are first gated on singlets, RBC exclusion, viable CD45\u003csup\u003e+\u003c\/sup\u003e cells, and FSC vs. SSC. CD3\u003csup\u003e-\u003c\/sup\u003e cells are gated and then divided to characterize myeloid lineage subsets by expression of CD11b, Ly6C, Ly6G, and F4\/80 and DC lineage subsets by expression of CD8, CD11c, B220, Ly6C, and CD4.\u003c\/p\u003e\u003cbr\u003e\u003cp\u003e\u003cb\u003eTube 3: Treg Identification Tube\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-3-Data-95-K301.png\" target=\"_blank\"\u003e\u003cimg alt=\"\" src=\"https:\/\/cytek-web.s3.us-east-1.amazonaws.com\/cytekbio.com\/Tonbo\/images\/95-K001\/Tube-3-Data-95-K301.png\"\u003e\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003e\u003cspan\u003eFigure 3: \u003c\/span\u003e\u003c\/strong\u003eTube 3 enables the identification of regulatory T cells (Tregs) in addition to characterization of immune checkpoint receptors and T cell activation. Intracellular staining of Foxp3 and CD152 is required. Events are first gated on singlets, RBC exclusion, and viable CD45\u003csup\u003e+\u003c\/sup\u003e cells. The CD45\u003csup\u003e+\u003c\/sup\u003eCD3\u003csup\u003e+\u003c\/sup\u003e cells are further gated by expression of CD4 and CD8. Within the CD4\u003csup\u003e+\u003c\/sup\u003e T cells, Tregs are identified by co-expression of CD25 and Foxp3. In the T helper (Th) and CD8\u003csup\u003e+\u003c\/sup\u003e populations, immune checkpoint receptor expression can be determined by gating on CD223 (Lag-3), CD279 (PD-1), and CD152 (CTLA-4) subsets while cell activation can be quantified using CD25 and CD69.\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eRECOMMENDED USAGE\u003c\/strong\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eDownload \u003ca rel=\"noopener\" title=\"Mouse TBNK\/Myeloid\/Treg Kit Sample Preparation\" href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/kit-documentation\/tonbo-mouse-kit\/Tonbo-Mouse-Kit-Guidelines.pdf\" target=\"_blank\"\u003eSample Preparation Guidelines for Cytek\u003csup\u003e®\u003c\/sup\u003e Tonbo\u003csup\u003e®\u003c\/sup\u003e Mouse TBNK\/Myeloid\/Treg Kit\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDownload \u003ca title=\"TBNK Template\" href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/TBNK%20(Tube%201).zip\" data-mce-href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/TBNK%20(Tube%201).zip\"\u003eTBNK (Tube 1) Template\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDownload \u003ca title=\"Myeloid Template\" href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/Myeloid%20(Tube%202).zip\" data-mce-href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/Myeloid%20(Tube%202).zip\"\u003eMyeloid (Tube 2) Template\u003c\/a\u003e\n\u003c\/li\u003e\n\u003cli\u003eDownload \u003ca title=\"Treg Template\" href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/Treg%20(Tube%203).zip\" data-mce-href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Tonbo%20Experiment%20Templates\/Treg%20(Tube%203).zip\"\u003eTreg (Tube 3) Template\u003c\/a\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFor Research Use Only. Not intended for use in diagnostic procedures.\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 Tests Kit","offer_id":40581172166692,"sku":"95-K001-T025","price":2851.0,"currency_code":"USD","in_stock":true},{"title":"100 Tests Kit","offer_id":40821056471076,"sku":"95-K001-T100","price":7127.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests TBNK Identification Tube","offer_id":40581172199460,"sku":"95-K101-T025","price":1196.0,"currency_code":"USD","in_stock":true},{"title":"100 Tests TBNK Identification Tube","offer_id":40821057552420,"sku":"95-K101-T100","price":2851.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests Myeloid Identification Tube","offer_id":40581172232228,"sku":"95-K201-T025","price":1196.0,"currency_code":"USD","in_stock":true},{"title":"100 Tests Myeloid Identification Tube","offer_id":40821058404388,"sku":"95-K201-T100","price":2851.0,"currency_code":"USD","in_stock":true},{"title":"25 Tests Treg Identification Tube","offer_id":40581172264996,"sku":"95-K301-T025","price":1196.0,"currency_code":"USD","in_stock":true},{"title":"100 Tests Treg Identification Tube","offer_id":40821058502692,"sku":"95-K301-T100","price":2851.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/files\/Symbol_Full_Color_-_PNG_RGB_large_f4dc0075-a859-4770-8159-6193ca9cc1be.png?v=1759257994"},{"product_id":"shutdown-fluid-1x","title":"Shutdown Fluid (1X)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/documentation-center\/TDS\/R8-59011+Rev.+B_TDS_Shutdown+Fluid+(1X).pdf\" target=\"_blank\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\nShutdown Fluid is provided as a ready-to-use 1X solution for long-term storage of Cytek Bioscience analyzers.  Add the contents of the Shutdown Fluid (1X) container to a clean auxiliary sheath tank and run a Long Clean cycle.  Download the SDS \u003ca href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Data%20Sheets\/Beads%20SDS%20and%20TDS\/R8-70011_Rev.A%20Shutdown%20Fluid%20(1X)%20SDS%20Forms.zip\" title=\"SDS\" target=\"_blank\"\u003ehere\u003c\/a\u003e, and the TDS \u003ca href=\"https:\/\/welcome.cytekbio.com\/hubfs\/Website%20Downloadable%20Content\/Data%20Sheets\/Beads%20SDS%20and%20TDS\/R8-59011%20Rev.%20A_TDS_Shutdown%20Fluid%20(1X).pdf\" title=\"Shutdown Fluid TDS link\"\u003ehere\u003c\/a\u003e!\u003c\/div\u003e\n\u003cdiv class=\"std\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"std\"\u003e\u003cstrong\u003eFor general laboratory use.\u003c\/strong\u003e\u003c\/div\u003e\n\u003cdiv class=\"std\"\u003e\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eShutdown Fluid (1X)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eTNB-4601\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\n\u003cp\u003e\u003c\/p\u003e\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"1500 mL","offer_id":40581172297764,"sku":"TNB-4601-L1500","price":122.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/1.png?v=1675104603"},{"product_id":"percp-anti-mouse-cd45-30-f11","title":"PerCP Anti-Mouse CD45 (30-F11)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-67-0451.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.\u003c\/p\u003e\n\u003cp\u003eThe 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP Anti-Mouse CD45 (30-F11)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e67-0451\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeukocyte Common Antigen, LCA, Ly-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e19264\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e30-F11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581172330532,"sku":"67-0451-U025","price":87.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581172363300,"sku":"67-0451-U100","price":257.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/67-0451.png?v=1675104605"},{"product_id":"violetfluor-500-anti-human-cd8a-okt8","title":"violetFluor™ 500 Anti-Human CD8a (OKT8)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0086.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe OKT8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.\u003c\/p\u003e\n\u003cp\u003eThe OKT8 antibody is widely used as a phenotypic marker for CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells. If used together with alternative antibodies Anti-Human CD8a clone RPA-T8 or Anti-Human CD8a clone Hit8a, the OKT8 antibody will not block binding of RPA-T8 or Hit8a.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD8a (OKT8)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0086\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eOKT8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2a \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172396068,"sku":"85-0086-T025","price":117.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172428836,"sku":"85-0086-T100","price":263.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0086.png?v=1675104607"},{"product_id":"percp-cyanine5-5-anti-human-hla-dr-l243","title":"PerCP-Cyanine5.5 Anti-Human HLA-DR (L243)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-65-9952.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5 Anti-Human HLA-DR (L243)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e65-9952\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e3122\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eL243\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2a, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee, Cynomolgus, Rhesus, Baboon, Squirrel Monkey, African Green Monkey\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172461604,"sku":"65-9952-T025","price":160.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172494372,"sku":"65-9952-T100","price":343.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/65-9952.png?v=1675104609"},{"product_id":"violetfluor-500-anti-human-cd3-okt3","title":"violetFluor™ 500 Anti-Human CD3 (OKT3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0037.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.\u003c\/p\u003e\n\u003cp\u003eThe OKT3 antibody is a widely used phenotypic marker for human T cells. In addition, as the CD3e subunit of the TCR complex contains intracellular signaling domains, binding of OKT3 antibody to CD3e can induce cell activation. A recent publication of the crystal structure of a CD3e-mitogenic antibody complex provides further insight as to the action of commonly used agonist antibodies, as well as specific epitope-binding data for the widely used human CD3 antibodies OKT3 and UCHT1 (Fernandes, R.A. et al. 2012. J. Biol. Chem. 287: 13324-13335). OKT3 has also been shown to be cross-reactive with Chimpanzee CD3 and has been used for in vitro activation of T cells in this species. Please choose the appropriate format for each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD3 (OKT3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0037\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-4, T3 \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e916\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eOKT3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2a, κ \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172559908,"sku":"85-0037-T025","price":96.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172592676,"sku":"85-0037-T100","price":235.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0037_1.png?v=1675104611"},{"product_id":"apc-anti-human-cd69-fn50","title":"APC Anti-Human CD69 (FN50)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-20-0699.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe FN50 monoclonal antibody reacts with human CD69, a type II transmembrane glycoprotein also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C. CD69 is expressed as a disulfide-linked homodimer on activated T and B cells, NK cells, neutrophils, and monocytes. Induction occurs rapidly upon activation and is transient. It is also constitutively expressed on platelets and a subset of thymocytes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC Anti-Human CD69 (FN50)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e20-0699\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eVery Early Activation Antigen (VEA), Activation inducer molecule (AIM)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e969\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFN50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1 k\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172625444,"sku":"20-0699-T025","price":62.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172658212,"sku":"20-0699-T100","price":147.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/20-0699.png?v=1675104613"},{"product_id":"pe-cyanine5-anti-human-cd4-rpa-t4","title":"PE-Cyanine5 Anti-Human CD4 (RPA-T4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-55-0049.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe RPA-T4 antibody is widely used as a phenotypic marker for human CD4 expression, and is cross-reactive with Chimpanzee CD4. This antibody recognizes a different epitope, and thus does not block binding of, the alternative Anti-Human CD4 antibody clone OKT4 (Reinherz EL, et al. 1979. Proc. Natl. Acad. Sci. 76:4061-4065).\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5 Anti-Human CD4 (RPA-T4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e55-0049\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRPA-T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172690980,"sku":"55-0049-T025","price":103.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172723748,"sku":"55-0049-T100","price":257.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/55-0049.png?v=1675104615"},{"product_id":"violetfluor-500-anti-mouse-cd45-1-a20","title":"violetFluor™ 500 Anti-Mouse CD45.1 (A20)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0453.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.\u003c\/p\u003e\n\u003cp\u003eThe A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL\/J, DA, STS\/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecent Publications:\u003c\/strong\u003e\u003cbr\u003e Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Mouse CD45.1 (A20) \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0453\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSJL, Ly5.1 \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e19264\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eA20\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2a, κ  \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581172756516,"sku":"85-0453-U025","price":121.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581172789284,"sku":"85-0453-U100","price":263.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0453.png?v=1675104617"},{"product_id":"violetfluor-500-anti-mouse-cd8a-2-43","title":"violetFluor™ 500 Anti-Mouse CD8a (2.43)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-1886.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 2.43 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death in tumor cells, as well as in cells infected by virus, bacteria or parasites.\u003c\/p\u003e\n\u003cp\u003eThe 2.43 antibody is widely used as a phenotypic marker for mouse CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Mouse CD8a (2.43)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-1886\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e12525\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e2.43\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581172822052,"sku":"85-1886-U025","price":103.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581172854820,"sku":"85-1886-U100","price":238.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-1886.png?v=1675104619"},{"product_id":"violetfluor-500-anti-mouse-cd4-gk1-5","title":"violetFluor™ 500 Anti-Mouse CD4 (GK1.5)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0041.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe GK1.5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the GK1.5 antibody and an alternative antibody, Anti-Mouse CD4 clone RM4-5, will “compete” for binding, i.e. RM4-5 is able to block GK1.5 binding to cells. In contrast, the Anti-Mouse CD4 clone RM4-4 does not block binding of the GK1.5 antibody to cells (Arora S et al. 2006. Infect. Immun. 74: 4339-4348). The GK1.5 antibody is also reported to be cross-reactive with Syrian hamster CD4.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Mouse CD4 (GK1.5)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0041\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eL3T4, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e12504\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eGK1.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSyrian Hamster\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581172887588,"sku":"85-0041-U025","price":103.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581172920356,"sku":"85-0041-U100","price":238.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0041.png?v=1675104621"},{"product_id":"violetfluor-450-anti-human-cd56-ncam-my31","title":"violetFluor™ 450 Anti-Human CD56 (NCAM) (MY31)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-75-0564.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.\u003c\/p\u003e\n\u003cp\u003eClone MY31 also reacts with a subset of CD14+ monocytes in non-human primates, and is reported to be cross-reactive with Chimpanzee, Cynomolgus and Rhesus.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450 Anti-Human CD56 (NCAM) (MY31)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e75-0564\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eneural cell adhesion molecule (NCAM), Leu-19\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e4684\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMY31\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee, Cynomolgus, Rhesus \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581172953124,"sku":"75-0564-T025","price":117.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581172985892,"sku":"75-0564-T100","price":263.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/75-0564.png?v=1675104623"},{"product_id":"violetfluor-450-anti-human-cd4-sk3","title":"violetFluor™ 450 Anti-Human CD4 (SK3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-75-0047.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450 Anti-Human CD4 (SK3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e75-0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSK3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCynomolgus, Rhesus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173018660,"sku":"75-0047-T025","price":103.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173051428,"sku":"75-0047-T100","price":257.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/75-0047.png?v=1675104625"},{"product_id":"violetfluor-450-anti-mouse-cd69-h1-2f3","title":"violetFluor™ 450 Anti-Mouse CD69 (H1.2F3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-75-0691.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe H1.2F3 antibody reacts with mouse CD69, a type II transmembrane glycoprotein also known as the Very Early Activation Antigen, EA-1, Leu23, Activation Inducer Molecule (AIM) and CLEC2C. CD69 is expressed as a 60 kDa disulfide-linked homodimer on activated T and B cells, NK cells, neutrophils and monocytes. Induction occurs rapidly upon activation. It is also constitutively expressed on platelets and a subset of thymocytes. CD69 acts as a co-stimulatory molecule involved in activation and proliferation of T cells, and may be a marker for thymocytes undergoing TCR-mediated positive selection.\u003c\/p\u003e\n\u003cp\u003eCo-stimulation with the H1.2F3 clone has been reported to enhance T cell and macrophage activation. Please choose the appropriate format for each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450 Anti-Mouse CD69 (H1.2F3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e75-0691\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eVery Early Activation Antigen (VEA), AIM, EA-1, Leu23, CLEC2C, MLR3, gp34\/28\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e12515\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eH1.2F3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173084196,"sku":"75-0691-U025","price":79.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173116964,"sku":"75-0691-U100","price":195.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/75-0691.png?v=1675104626"},{"product_id":"violetfluor-450-anti-mouse-fc-epsilon-receptor-i-alpha-fcer1-mar-1","title":"violetFluor™ 450 Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-75-5898.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfamily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.\u003c\/p\u003e\n\u003cp\u003eThe MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro \/ in vivo. Please choose the appropriate format for each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450 Anti-Mouse Fc epsilon Receptor I alpha (FceR1) (MAR-1)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e75-5898\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ehigh affinity IgE receptor\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e2205\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMAR-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 450\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173149732,"sku":"75-5898-U025","price":122.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173182500,"sku":"75-5898-U100","price":282.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/75-5898.png?v=1675104628"},{"product_id":"violetfluor-500-mouse-igg2b-isotype-control-mpc-11","title":"violetFluor™ 500 Mouse IgG2b Isotype Control (MPC-11)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-4732.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Mouse IgG2b Isotype Control (MPC-11)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-4732\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMPC-11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2b\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173215268,"sku":"85-4732-U025","price":185.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173248036,"sku":"85-4732-U100","price":380.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB.png?v=1675104631"},{"product_id":"violetfluor-500-anti-human-cd20-2h7","title":"violetFluor™ 500 Anti-Human CD20 (2H7)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0209.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 2H7 antibody reacts with human CD20, expressed by pre-B cells, resting and activated B cells, follicular dendritic cells and a small subset of T cells, but not on plasma cells. CD20 is a 33-37 kDa transmembrane protein which is differentially phosphorylated in resting and active B cells. The CD20 molecule plays a role in regulating B-cell activation.\u003c\/p\u003e\n\u003cp\u003eThe 2H7 antibody is reported to be cross-reactive with several non-human species including Baboon, Chimpanzee, Cynomolgus and Rhesus. Please choose the appropriate format for each application.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD20 (2H7)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0209\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eB1, Leu-16, Bp35\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e931\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e2H7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2b, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eBaboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Capuchin Monkey, Squirrel Monkey\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173280804,"sku":"85-0209-T025","price":166.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173313572,"sku":"85-0209-T100","price":368.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0209.png?v=1675104632"},{"product_id":"violetfluor-500-anti-human-cd4-sk3","title":"violetFluor™ 500 Anti-Human CD4 (SK3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0047.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD4 (SK3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSK3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCynomolgus, Rhesus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173346340,"sku":"85-0047-T025","price":160.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173379108,"sku":"85-0047-T100","price":368.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0047.png?v=1675104636"},{"product_id":"violetfluor-500-anti-human-cd16-3g8","title":"violetFluor™ 500 Anti-Human CD16 (3G8)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0166.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 3G8 monoclonal antibody reacts with the 50-65kD transmembrane form of human CD16 (FCGR3A). CD16 is the low affinity IgG receptor III and is expressed on NK cells and macrophages. CD16 participates in signal transduction and mediates antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells. The second form of CD16 (FCGR3B) is a glycosyl-phosphatidylinositol (GPI) linked molecule expressed exclusively on neutrophils.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\u003ctbod\u003e\u003c\/tbod\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD16 (3G8)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0166\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class-=\"\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCd16, FcγRIII\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e3G8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, k\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173411876,"sku":"85-0166-T025","price":177.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173444644,"sku":"85-0166-T100","price":306.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0166.png?v=1675104639"},{"product_id":"pe-cyanine7-anti-human-cd8-sk1","title":"PE-Cyanine7 Anti-Human CD8 (SK1)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-60-0087.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe SK1 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.\u003c\/p\u003e\n\u003cp\u003eThe SK1 antibody is widely used as a phenotypic marker for CD8 on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells. It is cross-reactive with CD8 in several non-human species, including Baboon, Chimpanzee, Cynomolgus and Rhesus. If used together with an alternative Anti-Human CD8a clone, RPA-T8, the SK1 antibody will not block binding of RPA-T8 to CD8a.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine7 Anti-Human CD8 (SK1)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e60-0087\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCD8 alpha, leu-2a\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e925\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSK1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAfrican Green, Baboon, Chimpanzee, Cynomolgus, Rhesus, Pigtailed Macaque, Sooty Mangabey\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173477412,"sku":"60-0087-T025","price":129.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173510180,"sku":"60-0087-T100","price":294.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/60-0087.png?v=1675104641"},{"product_id":"biotin-anti-mouse-ly-6g-1a8","title":"Biotin Anti-Mouse Ly-6G (1A8)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-30-1276.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 1A8 antibody binds to mouse Ly-6G, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. \u003cspan data-mce-fragment=\"1\"\u003eLy-6G \u003c\/span\u003eis differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.\u003c\/p\u003e\n\u003cp\u003eIn the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1\/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G\/Ly-6C.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eBiotin Anti-Mouse Ly-6G (1A8)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e30-1276\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e546644\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e1A8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2a, κκ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eBiotin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173542948,"sku":"30-1276-U025","price":41.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173575716,"sku":"30-1276-U100","price":101.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/30-1276.png?v=1675104643"},{"product_id":"redfluor-710-armenian-hamster-igg-isotype-control-pip","title":"redFluor™ 710 Armenian Hamster IgG Isotype Control (PIP)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-80-4888.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe PIP immunoglobulin is useful as an isotype-matched control. The PIP immunolglobulin is specific for Glutathione S-transferase and can be used as an isotype control for Armenian Hamster IgG antibodies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710 Armenian Hamster IgG Isotype Control (PIP)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e80-4888\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePIP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173674020,"sku":"80-4888-U025","price":87.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173706788,"sku":"80-4888-U100","price":214.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB_ea7d464b-a475-4c45-843a-c9539393aa4e.png?v=1675104645"},{"product_id":"redfluor-710-anti-human-cd4-rpa-t4","title":"redFluor™ 710 Anti-Human CD4 (RPA-T4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-80-0049.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe RPA-T4 antibody is widely used as a phenotypic marker for human CD4 expression, and is cross-reactive with Chimpanzee CD4. This antibody recognizes a different epitope, and thus does not block binding of, the alternative Anti-Human CD4 antibody clone OKT4 (Reinherz EL, et al. 1979. Proc. Natl. Acad. Sci. 76:4061-4065).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710 Anti-Human CD4 (RPA-T4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e80-0049\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRPA-T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173739556,"sku":"80-0049-T025","price":98.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173772324,"sku":"80-0049-T100","price":227.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/80-0049.png?v=1675104647"},{"product_id":"redfluor-710-anti-human-cd4-sk3","title":"redFluor™ 710 Anti-Human CD4 (SK3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-80-0047.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710 Anti-Human CD4 (SK3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e80-0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSK3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCynomolgus, Rhesus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173805092,"sku":"80-0047-T025","price":98.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173837860,"sku":"80-0047-T100","price":203.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/80-0047.png?v=1675104649"},{"product_id":"pe-cyanine5-anti-human-cd4-sk3","title":"PE-Cyanine5 Anti-Human CD4 (SK3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-55-0047.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe SK3 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe SK3 antibody is widely used as a phenotypic marker for human CD4 expression, and has been reported to be cross-reactive with Rhesus and Cynomolgus CD4. This antibody does not block binding of alternative clone RPA-T4, suggesting that they recognize different epitopes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5 Anti-Human CD4 (SK3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e55-0047\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eSK3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCynomolgus, Rhesus\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581173870628,"sku":"55-0047-T025","price":128.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581173903396,"sku":"55-0047-T100","price":268.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/55-0047.png?v=1675104654"},{"product_id":"apc-cyanine7-anti-mouse-tcr-beta-h57-597","title":"APC-Cyanine7 Anti-Mouse TCR beta (H57-597)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-25-5961.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma\/delta protein chains, known as the g\/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.\u003c\/p\u003e\n\u003cp\u003eThe H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g\/d TCR.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecent Publications:\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eBescucci DM, Clarke ST, Brown CLJ, et al. The absence of murine cathelicidin-related antimicrobial peptide impacts host responses enhancing Salmonella enterica serovar Typhimurium infection. Gut Pathog. 2020 Nov 13;12(1):53. doi: 10.1186\/s13099-020-00386-1. PMID: 33292444; PMCID: PMC7666523.\u003c\/p\u003e\n\u003cp\u003e\u003ca title=\"The absence of murine cathelicidin-related antimicrobial peptide impacts host responses enhancing Salmonella enterica serovar Typhimurium infection\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33292444\/\" target=\"_blank\"\u003e» View on PubMed\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eKarki R, Sharma BR, Lee E, et al. Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer. JCI Insight. 2020;5(12):136720. Published 2020 Jun 18. doi:10.1172\/jci.insight.136720.\u003c\/p\u003e\n\n\u003cp\u003eKondo M, Tanaka Y, Kuwabara T, Naito T, Kohwi-Shigematsu T and Watanabe A. 2015. J Immunol. doi: 10.4049\/jimmunol.1501429. (Flow Cytometry)\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7 Anti-Mouse TCR beta (H57-597)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e25-5961\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eTCRb, TCRbeta, TCR-b chain, TCR-b, b-TCR\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e21577\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eH57-597\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581173936164,"sku":"25-5961-U025","price":93.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581173968932,"sku":"25-5961-U100","price":215.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/25-5961.png?v=1675104656"},{"product_id":"percp-cyanine5-5-anti-mouse-cd45-30-f11","title":"PerCP-Cyanine5.5 Anti-Mouse CD45 (30-F11)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-65-0451.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.\u003c\/p\u003e\n\u003cp\u003eThe 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5 Anti-Mouse CD45 (30-F11)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e65-0451\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeukocyte Common Antigen, LCA, Ly-5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e19264\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e30-F11\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174001700,"sku":"65-0451-U025","price":79.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174034468,"sku":"65-0451-U100","price":209.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/65-0451.png?v=1675104658"},{"product_id":"percp-cyanine5-5-anti-mouse-ly-6c-hk1-4","title":"PerCP-Cyanine5.5 Anti-Mouse Ly-6C (HK1.4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-65-5932.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe HK1.4 monoclonal antibody reacts with mouse Ly-6C, a 15-17kD GPI-linked cell-surface protein. Ly-6C is expressed on monocyte\/macrophage cells, endothelial cells, granulocytes and a subset of lymphocytes. Mice strains with the Ly-6.2 alloantigen have subsets of both Ly-6C positive CD4 and CD8 cells while Ly-6.1 expressing strains have only the CD8 Ly-6C positive subset.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5 Anti-Mouse Ly-6C (HK1.4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e65-5932\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLy6C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e16398\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHK1.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2c, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174067236,"sku":"65-5932-U025","price":129.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174100004,"sku":"65-5932-U100","price":306.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/65-5932.png?v=1675104660"},{"product_id":"fixation-buffer","title":"Fixation Buffer","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-TNB-8222.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eFixation Buffer can be used to fix cells prior to permeabilization when performing intracellular staining for antigens expressed on cytoplasmic proteins. This buffer can also be used to fix cells after immunofluorescent staining when the acquisition of samples will be delayed.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFixation Buffer\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eTNB-8222\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 mL","offer_id":40581174132772,"sku":"TNB-8222-L100","price":50.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB_504dc17b-0719-4b32-8260-6b71835f6876.png?v=1675104662"},{"product_id":"apc-cyanine7-anti-mouse-nk1-1-cd161-pk136","title":"APC-Cyanine7 Anti-Mouse NK1.1 (CD161) (PK136)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-25-5941.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL\/6, FVB\/N, and NZB), yet absent from others (AKR, BALB\/c, CBA\/J, C3H, DBA\/1, DBA\/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+\/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).\u003c\/p\u003e\n\u003cp\u003eThe PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma\/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).\u003c\/p\u003e\n\u003cp\u003e \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecent Publications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eClark NM, Martinez LM, Murdock S, deLigio JT, Olex AL, Effi C, Dozmorov MG, Bos PD. Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells. Cell Rep. 2020 Dec 8;33(10):108482. doi: 10.1016\/j.celrep.2020.108482. PMID: 33296659.\u003c\/p\u003e\n\u003cp\u003e\u003ca title=\"Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124720314716\" target=\"_blank\"\u003e» View on ScienceDirect\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7 Anti-Mouse NK1.1 (CD161) (PK136)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e25-5941\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCD161, NKR-P1C, Ly-55\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e17059\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePK136\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2a, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174165540,"sku":"25-5941-U025","price":87.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174198308,"sku":"25-5941-U100","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/25-5941.png?v=1675104664"},{"product_id":"percp-anti-mouse-ly-6g-gr-1-rb6-8c5","title":"PerCP Anti-Mouse Ly-6G\/Ly-6C (Gr-1) (RB6-8C5)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-67-5931.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe RB6-8C5 antibody binds to mouse Ly-6G\/Ly-6C, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expressed at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.\u003c\/p\u003e\n\u003ch4\u003e\u003cstrong\u003eRecent Citations:\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eSugimoto Y, Endo D, Aratani Y. Mice Deficient in NOX2 Display Severe Thymic Atrophy, Lymphopenia, and Reduced Lymphopoiesis in a Zymosan-Induced Model of Systemic Inflammation. Inflammation. 2020 Sep 16. doi: 10.1007\/s10753-020-01342-6. PMID: 32939668.  \u003c\/p\u003e\n\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP Anti-Mouse Ly-6G (Gr-1) (RB6-8C5) \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e67-5931\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eGr1, Ly6G \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e17067\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRB6-8C5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ  \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174231076,"sku":"67-5931-U025","price":98.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174263844,"sku":"67-5931-U100","price":246.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/67-5931.png?v=1675104666"},{"product_id":"percp-anti-mouse-cd8a-53-6-7","title":"PerCP Anti-Mouse CD8a (53-6.7)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-67-0081.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.\u003c\/p\u003e\n\u003cp\u003eThe 53-6.7 antibody is widely used as a phenotypic marker for mouse CD8a expression on cytotoxic T cells, thymocytes, as well as on certain cell types that do not also express the TCR, including some NK cells and lymphoid dendritic cells.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecent Publications:\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eC Khouili S, Cook ECL, Hernández-García E, Martínez-López M, Conde-Garrosa R, Iborra S. SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity. Cell Rep. 2020 Dec 1;33(9):108468. doi: 10.1016\/j.celrep.2020.108468. PMID: 33264612.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca title=\"SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33264612\/\" target=\"_blank\"\u003e\u003cspan\u003e» View on PubMed\u003c\/span\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin: 0in; line-height: 14.65pt; outline: none; box-sizing: border-box; font-variant-ligatures: normal; font-variant-caps: normal; orphans: 2; text-align: start; widows: 2; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; word-spacing: 0px;\"\u003e \u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eHiroshi Kobayashi and Keiyo Takubo. Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells. STAR Protocols.  Published 2 August 2020. https:\/\/doi.org\/10.1016\/j.xpro.2020.100078. \u003c\/p\u003e\n\n\u003cp\u003eKobayashi H, Morikawa T, Okinaga A, et al. Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo. Cell Rep. 2019;28(1):145-158.e9. doi:10.1016\/j.celrep.2019.06.008.\u003c\/p\u003e\n\n\u003cp\u003eFinkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, Browning JL, Goossens N, Nakagawa S, Gunasekara G, Schwartz ME et al. 2015. Nat Immunol. doi: 10.1038\/ni.3290. (Flow Cytometry)\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP Anti-Mouse CD8a (53-6.7)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e67-0081\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e12525\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e53-6.7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2a, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174362148,"sku":"67-0081-U025","price":98.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174394916,"sku":"67-0081-U100","price":246.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/67-0081.png?v=1675104669"},{"product_id":"percp-anti-human-mouse-cd45r-b220-ra3-6b2","title":"PerCP Anti-Human\/Mouse CD45R (B220) (RA3-6B2)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-67-0452.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of ≥ 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R\/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB, CD45RO and several others.\u003c\/p\u003e\n\u003cp\u003eThe RA3-6B2 antibody is one of the most consistently used leukocyte markers for B cells, T cell subsets and NK cell subsets in human and mouse. This antibody has also been reported as cross-reactive with feline CD45R\/B220.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP Anti-Human\/Mouse CD45R (B220) (RA3-6B2)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e67-0452\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLy-5, Lyt-4, T200\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e19264\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRA3-6B2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2a, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman, Mouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFeline\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174427684,"sku":"67-0452-U025","price":98.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581174460452,"sku":"67-0452-U100","price":246.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/67-0452.png?v=1675104671"},{"product_id":"fastprobe-1-step-rt-qpcr-plus-no-rox-kit","title":"FastPROBE™ 1-Step RT-qPCR Plus No-ROX Kit","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-31-5243.pdf\"\u003eTDS\u003c\/a\u003e\u003c\/p\u003e\nFastPROBE™ 1-Step RT-qPCR Plus No-ROX Kit contains everything required for efficient cDNA synthesis and probe-based qPCR in a single tube using real-time instruments that do not require normalization with a ROX dye. This approach offers simplicity and convenience and minimizes the possibility for contamination. An integral component, the Classic++™ Hot Start \u003cem\u003eTaq\u003c\/em\u003e DNA Polymerase is compatible with all fluorogenic probes including hydrolysis and displacement probes such as TaqMan®, Scorpions® and Molecular Beacons probes. Novel hot start technology prevents primer dimer formation and non-specific amplification resulting in higher yields and specificity. 1-Step Kits include a proprietary M-MLV Reverse Transcriptase (RT) molecule blended with an optimized RNase inhibitor, providing increased specificity, higher yields of cDNA, and more full-length product than other reverse transcriptases. Our M-MLV RT is ultra-stable and highly active, working on varied and difficult templates. Convenient and reliable, Tonbo’s FastPROBE 1-Step RT-qPCR Plus No-ROX Kit is ideal for the sensitive and efficient quantification of RNA templates, including low copy number targets, under standard or fast cycling conditions. Use for for low copy number detection, microarray validation, SNP genotyping and multiplexing. Please refer to our Instrument Compatibility Guide to ensure you have the correct ROX concentration for your system.\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFastPROBE™ 1-Step RT-qPCR Plus No-ROX Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e31-5243\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePCR\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 rxns","offer_id":40581174558756,"sku":"31-5243-0100R","price":160.0,"currency_code":"USD","in_stock":true},{"title":"300 rxns","offer_id":40581174591524,"sku":"31-5243-0300R","price":428.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/icon-pcr-product_3_04bdbc0c-1b76-4a0e-880f-8e823601156c.png?v=1675104673"},{"product_id":"fastprobe-1-step-rt-qpcr-plus-lo-rox-kit","title":"FastPROBE™ 1-Step RT-qPCR Plus Lo-ROX Kit","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-31-5241.pdf\"\u003eTDS\u003c\/a\u003e\u003c\/p\u003e\nFastPROBE™ 1-Step RT-qPCR Plus Lo-ROX Kit contains everything required for efficient cDNA synthesis and probe-based qPCR in a single tube using real-time instruments that support normalization with a standard ROX passive reference dye at a final concentration of ≥ 50 nM. This approach offers simplicity and convenience and minimizes the possibility for contamination. An integral component, the Classic++™ Hot Start \u003cem\u003eTaq\u003c\/em\u003e DNA Polymerase is compatible with all fluorogenic probes including hydrolysis and displacement probes such as TaqMan®, Scorpions® and Molecular Beacons probes. Novel hot start technology prevents primer dimer formation and non-specific amplification resulting in higher yields and specificity. 1-Step Kits include a proprietary M-MLV Reverse Transcriptase (RT) molecule blended with an optimized RNase inhibitor, providing increased specificity, higher yields of cDNA, and more full-length product than other reverse transcriptases. Our M-MLV RT is ultra-stable and highly active, working on varied and difficult templates. Convenient and reliable, Tonbo’s FastPROBE 1-Step RT-qPCR Plus Lo-ROX Kit is ideal for the sensitive and efficient quantification of RNA templates, including low copy number targets, under standard or fast cycling conditions. Use for for low copy number detection, microarray validation, SNP genotyping and multiplexing. Please refer to our Instrument Compatibility Guide to ensure you have the correct ROX concentration for your system.\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFastPROBE™ 1-Step RT-qPCR Plus Lo-ROX Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e31-5241\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePCR\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 rxns","offer_id":40581174624292,"sku":"31-5241-0100R","price":160.0,"currency_code":"USD","in_stock":true},{"title":"300 rxns","offer_id":40581174657060,"sku":"31-5241-0300R","price":428.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/icon-pcr-product_1_d8163fc4-f35a-40c5-9ec9-e8613acb86a6.png?v=1675104675"},{"product_id":"fastprobe-1-step-rt-qpcr-plus-hi-rox-kit","title":"FastPROBE™ 1-Step RT-qPCR Plus Hi-ROX Kit","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-31-5242.pdf\"\u003eTDS\u003c\/a\u003e\u003c\/p\u003e\nFastPROBE™ 1-Step RT-qPCR Plus Hi-ROX Kit contains everything required for efficient cDNA synthesis and probe-based qPCR in a single tube using real-time instruments that support normalization with a standard ROX passive reference dye at a final concentration of ≥ 500 nM. This approach offers simplicity and convenience and minimizes the possibility for contamination. An integral component, the Classic++™ Hot Start \u003cem\u003eTaq\u003c\/em\u003e DNA Polymerase is compatible with all fluorogenic probes including hydrolysis and displacement probes such as TaqMan®, Scorpions® and Molecular Beacons probes. Novel hot start technology prevents primer dimer formation and non-specific amplification resulting in higher yields and specificity. 1-Step Kits include a proprietary M-MLV Reverse Transcriptase (RT) molecule blended with an optimized RNase inhibitor, providing increased specificity, higher yields of cDNA, and more full-length product than other reverse transcriptases. Our M-MLV RT is ultra-stable and highly active, working on varied and difficult templates. Convenient and reliable, Tonbo’s FastPROBE 1-Step RT-qPCR Plus Hi-ROX Kit is ideal for the sensitive and efficient quantification of RNA templates, including low copy number targets, under standard or fast cycling conditions. Use for for low copy number detection, microarray validation, SNP genotyping and multiplexing. Please refer to our Instrument Compatibility Guide to ensure you have the correct ROX concentration for your system.\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFastPROBE™ 1-Step RT-qPCR Plus Hi-ROX Kit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e31-5242\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePCR\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 rxns","offer_id":40581174689828,"sku":"31-5242-0100R","price":160.0,"currency_code":"USD","in_stock":true},{"title":"300 rxns","offer_id":40581174722596,"sku":"31-5242-0300R","price":428.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/icon-pcr-product_7d80090c-cfd6-4ee1-8fce-6f9109299c22.png?v=1675104677"},{"product_id":"goat-anti-rabbit-igg-h-l-affinity-pure-fitc-conjugate-cross-adsorbed-min-react","title":"Goat anti-Rabbit IgG (H\u0026L) - Affinity Pure, FITC Conjugate, Cross-Adsorbed, min reactivity","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-35-8068.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\nGoat anti-Rabbit IgG (H\u0026amp;L) - Affinity Pure, FITC Conjugate, min x w\/bovine, human, or mouse IgG\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eGoat anti-Rabbit IgG (H\u0026amp;L) - Affinity Pure, FITC Conjugate, Cross-Adsorbed\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e35-8068\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRabbit\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e Based on IEP, no reactivity is observed to: · non-immunoglobulin rabbit serum proteins · serum proteins from bovine, human, or mouse · IgG from human or mouse \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFITC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eSpecificity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRabbit IgG (H\u0026amp;L) \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eHost\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eGoat\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Adsorption\u003c\/th\u003e\n\u003ctd class=\"data\"\u003emin x w\/bovine, human, or mouse IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eConcentration\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e1.50 mg\/mL\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormulation\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 1 % (w\/v) BSA, Protease\/IgG free and 0.05% (w\/v) Sodium Azide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplications\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFC, IF, ELISA, Immunomicroscopy\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003ePurity (%)\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e\u0026gt;95% based on SDS-PAGE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"1 mg","offer_id":40581174755364,"sku":"35-8068-M001","price":202.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB_54ce6c83-4757-43d6-a70e-e43cdf7abd52.png?v=1675104679"},{"product_id":"in-vivo-ready-armenian-hamster-igg-isotype-control-pip","title":"In Vivo Ready™ Armenian Hamster IgG Isotype Control (PIP)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003eThe PIP immunoglobulin is useful as an isotype-matched control. The PIP immunolglobulin is specific for Glutathione S-transferase and can be used as an isotype control for Armenian Hamster IgG antibodies.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eIn Vivo Ready™ Armenian Hamster IgG Isotype Control (PIP)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e40-4888\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth class=\"label\"\u003eData Sheets\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e\n\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-40-4888.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePIP\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eIn Vivo Ready™\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFC - Validated\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cspan data-mce-fragment=\"1\"\u003e\u003cb\u003eFor Research Use Only. Not intended for use in diagnostic procedures.\u003c\/b\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 µg","offer_id":40581174788132,"sku":"40-4888-U100","price":50.0,"currency_code":"USD","in_stock":true},{"title":"500 µg","offer_id":40581174820900,"sku":"40-4888-U500","price":121.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB_23023ce1-1033-4a7f-84c1-ca67bd8475be.png?v=1675104681"},{"product_id":"apc-cyanine7-anti-human-cd14-61d3","title":"APC-Cyanine7 Anti-Human CD14 (61D3)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-25-0149.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7 Anti-Human CD14 (61D3)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e25-0149\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLPS-R, Mo2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e929\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e61D3\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC-Cyanine7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581174853668,"sku":"25-0149-T025","price":141.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581174886436,"sku":"25-0149-T100","price":300.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/25-0149.png?v=1675104683"},{"product_id":"percp-cyanine5-5-anti-human-cd56-ncam-my31","title":"PerCP-Cyanine5.5 Anti-Human CD56 (NCAM) (MY31)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-65-0564.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.\u003c\/p\u003e\n\u003cp\u003eClone MY31 also reacts with a subset of CD14+ monocytes in non-human primates, and is reported to be cross-reactive with Chimpanzee, Cynomolgus and Rhesus.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5 Anti-Human CD56 (NCAM) (MY31)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e65-0564\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eneural cell adhesion molecule (NCAM), Leu-19\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e4684\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMY31\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee, Cynomolgus, Rhesus \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePerCP-Cyanine5.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581174919204,"sku":"65-0564-T025","price":153.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581174951972,"sku":"65-0564-T100","price":362.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/65-0564.png?v=1675104685"},{"product_id":"copy-of-redfluor-710-anti-mouse-cd11c-n418","title":"redFluor™ 710 Anti-Mouse CD48 (HM48-1)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-80-0481.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe HM48-1 monoclonal antibody reacts with mouse CD48, a 45 kDa GPI-anchored glycoprotein that is also known as BCM1. CD48 is a member of the signaling lymphocyte activation molecule (SLAM) family and Ig superfamily. It is expressed on leukocytes, but not on non-hematopoietic cells and plays a role in cell adhesion and activation. The primary ligands for CD48 are CD2 (LFA-2) and CD244 (2B4 antigen).  The HM48-1 antibody is reported to block in vitro and in vivo CD48 mediated interactions.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710 Anti-Mouse CD48 (HM48-1)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e80-0481\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHM48-1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eArmenian Hamster IgG\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eredFluor™ 710\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581174984740,"sku":"80-0481-U025","price":93.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175017508,"sku":"80-0481-U100","price":214.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/80-0481.png?v=1675104687"},{"product_id":"biotin-anti-mouse-cd24-m1-69","title":"Biotin Anti-Mouse CD24 (M1\/69)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-30-0242.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe M1\/69 antibody reacts with mouse CD24, a cell surface molecule also known as Heat Stable Antigen (HSA). CD24 is a GPI-linked glycoprotein involved in cell adhesion and is a ligand for CD62P (P-selectin). It is expressed on erthrocytes, thymocytes, peripheral lymphocytes and myeloid lineage cells. The expression of CD24 is used to delineate stages of of lymphocyte development in the bone marrow.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eBiotin Anti-Mouse CD24 (M1\/69)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e30-0242\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHeat Stable Antigen, HSA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e12484\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eM1\/69\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eBiotin\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175050276,"sku":"30-0242-U025","price":31.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175083044,"sku":"30-0242-U100","price":79.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/30-0242.png?v=1675104689"},{"product_id":"pe-cyanine5-anti-mouse-cd25-pc61-5","title":"PE-Cyanine5 Anti-Mouse CD25 (PC61.5)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-55-0251.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe PC61.5 antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-. This clone has also been reported for depletion of Treg cells in vivo (use format suitable for functional assays).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRecent Publications:\u003c\/strong\u003e\u003cbr\u003e Ortega SB, Noorbhai I, Poinsatte K, Kong X, Anderson A, Monson NL and Stowe AM. 2015. Discov Med. 19(106): 381-392. (Flow Cytometry)\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5 Anti-Mouse CD25 (PC61.5)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e55-0251\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eInterleukin-2 Receptor alpha, IL-2Rα, Ly-43, p55, Tac  \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e16184\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePC61.5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG1, lambda \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175115812,"sku":"55-0251-U025","price":97.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175148580,"sku":"55-0251-U100","price":243.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/55-0251.png?v=1675104691"},{"product_id":"pe-cyanine5-anti-mouse-cd62l-l-selectin-mel-14","title":"PE-Cyanine5 Anti-Mouse CD62L (L-Selectin) (MEL-14)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-55-0621.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin αfamily of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.\u003c\/p\u003e\n\u003cp\u003eThe MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5 Anti-Mouse CD62L (L-Selectin) (MEL-14)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e55-0621\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLECAM-1, Ly-22\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e20343\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMEL-14\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2a, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine5\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175181348,"sku":"55-0621-U025","price":93.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175214116,"sku":"55-0621-U100","price":220.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/55-0621.png?v=1675104694"},{"product_id":"apc-anti-mouse-ly-6c-hk1-4","title":"APC Anti-Mouse Ly-6C (HK1.4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-20-5932.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe HK1.4 monoclonal antibody reacts with mouse Ly-6C, a 15-17kD GPI-linked cell-surface protein. Ly-6C is expressed on monocyte\/macrophage cells, endothelial cells, granulocytes and a subset of lymphocytes. Mice strains with the Ly-6.2 alloantigen have subsets of both Ly-6C positive CD4 and CD8 cells while Ly-6.1 expressing strains have only the CD8 Ly-6C positive subset.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC Anti-Mouse Ly-6C (HK1.4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e20-5932\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLy6C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e16398\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHK1.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2c, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eAPC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175246884,"sku":"20-5932-U025","price":116.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175279652,"sku":"20-5932-U100","price":286.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/20-5932.png?v=1675104696"},{"product_id":"purified-anti-human-cd16-3g8","title":"Purified Anti-Human CD16 (3G8)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-70-0166.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe 3G8 monoclonal antibody reacts with the 50-65kD transmembrane form of human CD16 (FCGR3A). CD16 is the low affinity IgG receptor III and is expressed on NK cells and macrophages. CD16 participates in signal transduction and mediates antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells. The second form of CD16 (FCGR3B) is a glycosyl-phosphatidylinositol (GPI) linked molecule expressed exclusively on neutrophils.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\u003ctbod\u003e\u003c\/tbod\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePurified Anti-Human CD16 (3G8)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e70-0166\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class-=\"\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eCd16, FcγRIII\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e3G8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG1, k\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePurified\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"100 ug","offer_id":40581175312420,"sku":"70-0166-U100","price":117.0,"currency_code":"USD","in_stock":true},{"title":"500 ug","offer_id":40581175345188,"sku":"70-0166-U500","price":324.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/Symbol_Full_Color_-_PNG_RGB_bb2c8ea5-e5d7-4bcf-88a2-389d0d988bf2.png?v=1675104698"},{"product_id":"violetfluor-500-anti-human-cd4-okt4","title":"violetFluor™ 500 Anti-Human CD4 (OKT4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003eThe OKT4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.\u003c\/p\u003e\n\u003cp\u003eThe OKT4 antibody is widely used as a phenotypic marker for CD4 expression. It is cross-reactive with CD4 in several non-human species, including Chimpanzee, Cynomolgus and Rhesus. This antibody recognizes a different epitope, and thus does not block binding of, the alternative Anti-Human CD4 antibody clone RPA-T4 (Reinherz EL, et al. 1979. Proc. Natl. Acad. Sci. 76:4061-4065)\u003c\/p\u003e\n\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e\u003cstrong\u003ePRODUCT DETAILS\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500 Anti-Human CD4 (OKT4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eSKU\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e85-0048\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eData Sheets\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e\n\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-85-0048.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eSDS\u003c\/a\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e  \n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLeu-3, T4 \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e920\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eOKT4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse IgG2b, kappa \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCross Reactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eChimpanzee, Cynomolgus, Rhesus  \u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003evioletFluor™ 500\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e \u003cbr\u003e \u003cb\u003eFor Research Use Only. Not intended for use in diagnostic procedures.\u003c\/b\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 tests","offer_id":40581175377956,"sku":"85-0048-T025","price":109.0,"currency_code":"USD","in_stock":true},{"title":"100 tests","offer_id":40581175410724,"sku":"85-0048-T100","price":269.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/85-0048.png?v=1677026837"},{"product_id":"pe-cyanine7-anti-mouse-mhc-class-ii-i-a-i-e-m5-114-15-2","title":"PE-Cyanine7 Anti-Mouse MHC Class II (I-A\/I-E) (M5\/114.15.2)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-60-5321.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe M5\/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7.\u003c\/p\u003e\n\u003cp\u003eThe M5\/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5\/114.15.2 clone may also be referred to as M5\/114 in the literature.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e\n\u003ccol width=\"25%\"\u003e\n\u003ccol\u003e\n\u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine7 Anti-Mouse MHC Class II (I-A\/I-E) (M5\/114.15.2)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e60-5321\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMHC II, IA, IE, I-A\/E, IA\/IE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e14961\/14969\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eM5\/114.15.2\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2b, κ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE-Cyanine7\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003edecorateTable('product-attribute-specs-table')\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175443492,"sku":"60-5321-U025","price":94.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175476260,"sku":"60-5321-U100","price":292.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/60-5321.png?v=1675104702"},{"product_id":"pe-anti-mouse-ly-6c-hk1-4","title":"PE Anti-Mouse Ly-6C (HK1.4)","description":"\u003cdiv class=\"std\"\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/TDS\/tds-50-5932.pdf\"\u003eTDS\u003c\/a\u003e | \u003ca href=\"https:\/\/cytek-web.s3.amazonaws.com\/cytekbio.com\/Tonbo\/SDS\/SDS_Pure\u0026amp;Conjugated%20Ab,%20and%20SA.pdf\"\u003eSDS\u003c\/a\u003e\u003c\/p\u003e\n\n\n\u003cp\u003eThe HK1.4 monoclonal antibody reacts with mouse Ly-6C, a 15-17kD GPI-linked cell-surface protein. Ly-6C is expressed on monocyte\/macrophage cells, endothelial cells, granulocytes and a subset of lymphocytes. Mice strains with the Ly-6.2 alloantigen have subsets of both Ly-6C positive CD4 and CD8 cells while Ly-6.1 expressing strains have only the CD8 Ly-6C positive subset.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003ctab\u003e\n\u003ctable class=\"data-table\" id=\"product-attribute-specs-table\"\u003e\n\u003ccolgroup\u003e \u003ccol width=\"25%\"\u003e \u003ccol\u003e \u003c\/colgroup\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eName\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE Anti-Mouse Ly-6C (HK1.4)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eCat. No.\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e50-5932\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eAlternative Names\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eLy6C\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eGene ID\u003c\/th\u003e\n\u003ctd class=\"data\"\u003e16398\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eClone\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eHK1.4\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eIsotype\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eRat IgG2c, kappa\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eReactivity\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eMouse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eFormat\u003c\/th\u003e\n\u003ctd class=\"data\"\u003ePE\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003cth class=\"label\"\u003eApplication\u003c\/th\u003e\n\u003ctd class=\"data\"\u003eFlow Cytometry\u003c\/td\u003e\n\u003c\/tr\u003e\n\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cscript type=\"text\/javascript\"\u003e\/\/ \u003c![CDATA[\ndecorateTable('product-attribute-specs-table')\n\/\/ ]]\u003e\u003c\/script\u003e\n\u003c\/tab\u003e","brand":"Tonbo Biosciences","offers":[{"title":"25 µg","offer_id":40581175509028,"sku":"50-5932-U025","price":69.0,"currency_code":"USD","in_stock":true},{"title":"100 µg","offer_id":40581175541796,"sku":"50-5932-U100","price":171.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1654\/6801\/products\/50-5932.png?v=1675104704"}],"url":"https:\/\/cytekbio.com\/ja\/collections\/tonbo-reagents\/leu4.oembed?page=2","provider":"Cytek Biosciences","version":"1.0","type":"link"}